Squamous cell carcinoma (SCC) is the second-most common malignant cutaneous cancer, with 60% occurring in the head and neck region. Metastases are uncommon and imply a more conservative prognosis. This report describes a case of parotid-invasive, facial squamous cell carcinoma, highlighting the importance of its prognostic and therapeutic management. The patient is an 81-year-old female, exhibi...

PATIENT 1 65 y/o M with history of previous resection of cutaneous SCCa of right cheek. Presented to clinic in 2008 with two year history of progressive right facial weakness, diplopia and pain in a trigeminal distribution. Had already undergone craniotomy with nondiagnostic biopsy because of concerns regarding cavernous sinus. On exam had right ophthalmoplegia and facial paralysis; no obvious ...

The most common gastrointestinal involvement in neurofibromatosis is due to tumoral lesions which may present with gastrointestinal bleeding or obstruction. We report a case of concurrent ulcerative colitis and neurofibromatosis.A 39 year-old woman, known case of neurofibromatosis, was admitted to our department with complaint of chronic bloody diarrhea. After thorough clinical examination and ...

OBJECTIVES AND DESIGN We performed a prospective study using magnetic resonance imaging (MRI) at regular post-operative intervals in non-irradiated patients with non-functioning pituitary adenomas (NFAs) to assess the frequency of tumoral regrowth and recurrences, in order to define the indications of post-operative radiotherapy. PATIENTS AND METHODS Fifty-one patients aged 25--80 years (mean...

In addition to its well-known homoeostatic actions in the cardiovascular system, ET-1 has been shown to constitute a potent growth regulatory peptide in various tissues. We have studied the expression of ET-1 and its receptors (ETAr and ET-Br) in human meningiomas (n = 35) as well as their involvement in cellular growth. By PCR of reversetranscribed RNA we detected ET-1 mRNA in 91% (32 of 35), ...

Abstract Background Langerhans cell histiocytosis (LCH) is an abnormal polyclonal proliferation of cells that affect different parts the body. Temporal bone involvement quite common among involved sites. The etiology unknown. Diagnosis based on symptoms, imaging, and histopathology. Especially LCH in temporal confused with acute or subacute otitis media. There are many treatment options LCH. Ca...

Increasing evidence suggests that E-selectin contributes to tumor growth and metastasis. E-selectin may increase tumoral angiogenesis and the adhesion of tumoral cells to endothelial cells at distant sites. The aim of this study was to assess the relationship between concentrations of circulating soluble E-selectin (sE-selectin) and clinical, pathological, and biological features in patients wi...

purpose : primary localized amyloidosis of eyelid is a localized type of amyloidosis without evidence of systemic involvement, which is a quite rare clinical condition. here we report a case of primary localized amyloidosis of eyelid. case report : a 40-year-old woman presented with a four-month history of swelling of the left upper eyelid resulting in a mechanical ptosis. the mass had a firm b...

Among clinicians, it is common practice to include parents in treatment, and it has been taken for granted that parents' involvement in their children's treatment is beneficial for therapy outcome, although research on this issue is far from clear. A meta-analysis was carried out in order to investigate whether parent involvement potentiates the outcome for children with anxiety disorders when ...