Deformable 3D dosimeters have potential applications in validating deformable dose mapping algorithms. This study evaluates a novel deformable PRESAGE® dosimeter and its application toward validating the deformable algorithm employed by VelocityAI. The deformable PRESAGE® dosimeter exhibited a linear dose response with a sensitivity of 0.0032 ΔOD/(Gy/cm). Comparison of an experimental dosimeter...

background: in order to deliver the precise dose to the target in radiotherapy, absorbed dose to water at the reference point should be assessed. when the calibration procedure is performed for a reference dosimeter in the 60co beam of a secondary standard dosimetry laboratory (ssdl), the total uncertainty in absorbed dose to water (dw) is estimated to be approximately 1.5%. this study attempts...

The scintillator with optical fiber (SOF) dosimeter consists of a miniature scintillator mounted on the tip of an optical fiber. The scintillator of the current SOF dosimeter is a 1-mm diameter hemisphere. For a scintillation dosimeter coupled with an optical fiber, measurement accuracy is influenced by signals due to Cerenkov radiation in the optical fiber. We have implemented a spectral filte...

Computed tomography (CT) has been widely used in clinical diagnosis. It is important to estimate radiation dose and perform image quality assurance procedures for CT scans. In this study, nMAG gel dosimeters were used to simultaneously measure the 300-mm weighted CT dose index (CTDI) and slice sensitivity profile (SSP) for multiple detector CT (MDCT). Magnetic resonance imaging (MRI) was perfor...

OBJECTIVES/HYPOTHESIS Voice rest is frequently recommended following surgical disruption of vocal fold epithelium, but patients report variable adherence to voice rest recommendations. The objective of this study was to assess the clinical utility of an ambulatory vocal dosimeter for measuring adherence to voice rest recommendations. STUDY DESIGN Outcomes research. METHODS Part 1: To determ...

Cyclins regulate progression through the cell cycle. Control of cyclin levels is essential in Drosophila oogenesis for the four synchronous divisions that generate the 16 cell germ line cyst and for ensuring that one cell in each cyst, the oocyte, is arrested in meiosis, while the remaining fifteen cells become polyploid nurse cells. Changes in cyclin levels could be achieved by regulating tran...

Currently, the use of blood irradiation for inactivating pathogenic microbes in infected blood products and preventing graft-versus-host disease (GVHD) in immune suppressed patients is greater than ever before. In these systems, dose distribution and uniformity are two important concepts that should be checked. In this study, dosimetry of the gamma chamber blood irradiator model Gammacell 3000 ...

Abstract. Gel dosimeters are integrating dosimeters, that enable dose verification in three dimensions. Optical analysis of gel dosimeters has demonstrated to be an available technique for imaging the absorbed in-phantom dose exposed to radiotherapy beams. The goal is to demonstrate the ability of gel dosimeters to achieve accurately and spatial resolution in dose mapping, also when high dose r...

A new inhalation synchronised dosimeter triggered by low inspiratory flow rates has been assessed. The methacholine challenge test using dosimeter nebulisation with controlled tidal breathing was compared with continuous nebulisation using De Vilbiss No 40 nebulisers with deep inhalations in 11 asthmatic subjects. Within subject PD20 FEV1 values were lower with the dosimeter method than with th...

The uncertainty of the beam quality conversion factor (k(Q,Q0)) of standard dosimetry of absorbed dose to water in external beam radiotherapy 12 (JSMP12) is determined by combining the uncertainty of each beam quality conversion factor calculated for each type of ionization chamber. However, there is no guarantee that ionization chambers of the same type have the same structure and thickness, s...