type 1 diabetes mellitus

Background: Type 1 Diabetes (T1D) is a chronic and progressive autoimmune disorder. Cytokines play a critical role in the pathogenesis of T1D. Objective: IFN-¹ polymorphism was investigated in T1D and compared with normal controls. Methods: Thirty patients suffering from T1D and 40 normal controls were studied simultaneously using PCR technique. IFN- ¹ gene was evaluated at position 5’UTR...

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altered concentrations of copper, zinc, and iron are associated with increased levels of glycated hemoglobin in patients with type 2 diabetes mellitus and their first-degree relatives

Journal: :international journal of endocrinology and metabolism 0

somayeh atari-hajipirloo department of biochemistry, urmia university of medical sciences, urmia, ir iran neda valizadeh department of endocrinology and metabolism, urmia university of medical sciences, urmia, ir iran mohammad-hassan khadem-ansari department of biochemistry, urmia university of medical sciences, urmia, ir iran yousef rasmi department of biochemistry, faculty of medicine, cellular and molecular research center, urmia university of medical sciences, urmi, ir iran fatemeh kheradmand department of biochemistry, faculty of medicine, cellular and molecular research center, urmia university of medical sciences, urmi, ir iran; department of biochemistry, faculty of medicine, cellular and molecular research center, urmia university of medical sciences, urmia, ir iran. tel: +98-4432770397, fax: +98-4432780801

background the altered levels of some essential trace elements and antioxidant minerals have been observed in diabetic patients. objectives the aim of the present study was to compare the concentrations of essential trace elements, copper (cu), zinc (zn), and iron (fe) in the serum of patients who have type 2 diabetes mellitus (t2dm) with those of their non-diabetic first-degree relatives (fdr)...

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