Tomato was evaluated for its liver protective role against carbon tetrachloride (CCl ) induced liver 4 damage in Wister albino rats. Animals were orally treated with tomato pulp (20 and 40 mL/kg body weight) for seven days followed by intraperitoneal injection (2 ml/kg) of 50% v/v CC1 on the last day. The degree of 4 protection was determined by measuring levels of serum biochemical parameters ...

This study tested the hypothesis that depressor responses caused by tempol are not associated with reductions in vascular O2- levels in urethane-anesthetized deoxycorticosterone acetate (DOCA)-salt hypertensive rats. We compared the effects of intravenous (IV) administration of tempol, apocynin, superoxide dismutase-polyethylene glycol (PEG-SOD), and SOD on mean arterial blood pressure (MAP), h...

The present study aimed to investigated the assessed total content of Arsenics, Ba, Pb, Rb, Sn, Sr, U and V in serpentinitic soils rocks that wide spread over Penjwin Mawat area Sulaymaniyah governorate/ Kurdistan region Iraq. This research was carried out during seasons 2018-2019 seven pedons (1, 2 3 from area, 4,5, 6, 7 area) chosen according variation chemical composition parent materials so...

BACKGROUND The optimal degree of heparin anticoagulation for peripheral vascular interventions (PVIs) has not been defined. We sought to correlate total heparin dose and peak procedural activated clotting time (ACT) with postprocedural outcomes in patients undergoing PVI. METHODS AND RESULTS We studied 4743 patients who received heparin during PVIs in a regional, multicenter registry. From th...

Two experiments were conducted to examine the impact of source, urea (U) or Optigen II (OP), and level of dietary NPN on performance (Exp.1) and N balance (Exp. 2) of growing cattle. Sixty Angus crossbred steers (initial BW = 353 ± 13.9 kg) were used to evaluate performance, and fed 1 of 3 steam-flaked corn based diets: U (U(1.2), 1.2% NPN), OP (OP(1.3), 1.3% NPN), or OP without cottonseed meal...

Erythropoietin (Epo) is a pleotropic cytokine with several nonhematopoietic tissue effects. High-dose Epo treatment-mediated effects on body weight, fat mass and glucose tolerance have recently been reported, thus extending its pleotropic effects to fat and glucose metabolism. However, the exact dose range of Epo treatment required for such effects remains unidentified to date. We investigated ...

INTRODUCTION Treatment with recombinant human erythropoietin enabled the correction of anemia in the patients on regular hemodialysis but large individual differences in the dose required to achieve the target hemoglobin level were observed. In this study the erythropoietin resistance index was calculated in patients on hemodialysis in order to examine variations in the response to erythropoiet...

BACKGROUND Although botulinum toxin is a well-established treatment of focal spasticity in cerebral palsy, most trials have been small, and few have simultaneously assessed measures of muscle tone and clinical benefit. METHODS Global, randomized, controlled study to assess the efficacy and safety of abobotulinumtoxinA versus placebo in cerebral palsy children with dynamic equinus foot deformi...

The clinical pharmacology of human recombinant erythropoietin (epoetin) was studied in order to compare the effectiveness of various routes and dosing schedules in dialysis patients. Thirty-six patients received epoetin beta three times a week i.v. for at least 12 wk. The mean dose needed to achieve target hemoglobin was 225 +/- 36 U/kg per week (median dose, 180 U/kg per week). Twenty-eight of...

The effects of human urinary trypsin inhibitor (UTI) were studied in experimental shock models. Administration of 50,000 U/kg, i.v., of UTI protected against mortality from shock induced by burn, endotoxin or trauma. Aprotinin at a dose of 50,000 U/kg improved only endotoxin shock and showed a moderate but not significant effect on burn and traumatic shock. Administration of 50,000 U/kg, i.v., ...