نتایج جستجو برای: u notch
تعداد نتایج: 183508 فیلتر نتایج به سال:
1. Abstract 2. Introduction 3. Notch signaling pathway 3.1. Notch receptors and ligands 3.2. Notch signaling activation 3.3. Notch signaling targets 4. Notch signaling in tumorigenesis 4.1. Cell proliferation 4.2. Cell survival (apoptosis evasion) 4.3. Angiogenesis 4.4. Cell invasion and metastasis 4.5. Notch and viral oncogenes 4.5.1. EBV viral protein EBNA2 and Notch 4.5.2. HPV viral protein ...
This paper discusses an elliptical ultrawideband (UWB) antenna and a dual-band UWB notch antenna. To achieve bandwidth, two corner cuts are etched into the rectangular slot on partial ground plane. An inverted-U-shaped conductor-shaped resonator utilized to characteristics The suggested has overall dimension of 24×32 mm2. gain 4.9 dB, bandwidth 2.5–11 GHz, linear phase response, group delay les...
The Notch signaling pathway governs many distinct cellular processes by regulating transcriptional programs. The transcriptional response initiated by Notch is highly cell context dependent, indicating that multiple factors influence Notch target gene selection and activity. However, the mechanism by which Notch drives target gene transcription is not well understood. Herein, we identify and ch...
This study investigated the roles of Notch‑1 in colorectal carcinoma, to assess the mechanisms. The expression of Notch‑1 and its ligand-Jagged1 was detected in human colorectal carcinoma, colorectal adenoma, paracancerous tissue and normal colorectal tissue by immunohistochemistry. Colorectal carcinoma cell lines were utilized to confirm the expression of Notch‑1 in colorectal carcinoma cells....
The principal difference between the small punch (SP) testing technique and standardized impact testing lies in the fact that the SP tests carried out in accordance with CWA 15627 Small Punch Test Method for Metallic Materials use disc-shaped test specimens without a notch. Especially in tough materials, the temperature dependence of SP fracture energy ESP in the transition area is very steep a...
Notch signal transduction is mediated by proteolysis of the receptor and translocation of the intracellular domain (IC) into the nucleus, where it functions as a regulator of HES gene expression after binding to the DNA-binding protein RBP-J kappa. The mammalian Notch receptors are structurally very similar, but have distinct functions. Most notably, Notch 1 IC is a potent activator of the HES ...
A coplanar waveguide (CPW) fed ultra-wideband (UWB) antenna with flexible and wide tunable dual bandnotched characteristics is proposed in this paper. The dual band-notched function is achieved by using an U-shaped slot inserted into the ellipse radiation patch and by using an elliptic parasitic slit placed near the ground plane. The wide tunable band-notched characteristic is implemented by ad...
A compact ultrawideband (UWB) monopole antenna with two U-shaped slots for WLAN and WiMAX dual band-notched functions is proposed and experimentally studied. The proposed antenna with the size of 28mm × 24mm × 1.6mm is excited by a 50Ω microstrip feed line. The band-notch functions are realized by loading two approximate half-wavelength U-shaped slots which change the current distribution on th...
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