AIMS This single-blinded, randomized, placebo-controlled study was designed and undertaken to assess the efficacy of intravenous atropine administration on haemodynamic impairment induced by head-up tilt testing in patients with vasovagal syncope. METHODS AND RESULTS One hundred and thirteen consecutive patients (62 male and 51 female, mean age 46.3 years) with recurrent syncope, no evidence ...

Sublingual nitroglycerin (TNG) has been introduced as a promising provocative agent for tilt table testing, but it has not been compared directly with the standard isoproterenol (ISO) infusion test previously. We tried to assess the diagnostic value and safety of TNG tilt testing as compared with ISO infusion in patients with unexplained syncope. TNG and ISO tilt tests were performed in tw...

we discuss here an uncommon condition of neurogenic hypotension in the context of immunoglobulin light chain (amyloid light-chain) amyloidosis. th e most serious feature was autonomic nervous system impairment, mainly characterized by severe refractory orthostatic hypotension, which became progressively invalidating, forcing the patient to bed. moreover, since the systemic involvement of the di...

OBJECTIVE To determine the role of the cerebral cortex in neurally mediated syncope, the electroencephalograms (EEG) of patients recorded during head up tilt table test were analysed. DESIGN Retrospective study. SETTING University hospital. PATIENTS 18 patients with syncope or near syncope underwent head up tilt table test with simultaneous ECG and EEG monitoring. METHODS Standard 70 de...