below), the emphasis for differentiating HUS from TTP has shifted from the pattern of clinical involvement to the presence or absence of the enzyme deficiency. It is now suggested that the diagnosis of TTP should be used to describe only those patients who have this enzyme deficiency; while patients without the enzyme deficiency should be labeled as suffering from HUS.4 ETIOLOGY AND PATHOGENESI...

One hundred and thirty-one patients on long-term hemodialysis were examined for the presence of clinical symptoms and signs, and for the effects of dialytic age, age and sex on uremic neuropathy. According to dialysis age, the patients were divided into three subgroups: low dialysis age, < 5 years of dialysis (n = 58); intermediate dialysis age, 5-10 years of hemodialysis (n = 39); and high dia...

CONTEXT Hemolytic uremic syndrome (HUS) is a severe acute disease, sometimes with long-term sequelae. The diarrhoea-unrelated forms are particularly associated with a poor prognosis. The aim of this paper is to review current evidence regarding etiology and management, and explore methods by which the outcome may be optimized. EVIDENCE ACQUISITION An internet search of Medline, Medscape, MDCo...

접수 : 2007년 8월 23일, 승인 : 2007년 9월 13일 책임저자: 박혜원, 포천중문의대 소아과학교실 Correspondence: Hye Won Park, M.D. Tel : 031)780-5230 Fax : 031)780-5239 E-mail : [email protected] 하 등을 특징으로 하는 드문 질환으로 영아나 어린 소아의 급성 신부전의 가장 흔한 원인이다 1, 2) . 미세혈관병증 용혈성 빈혈의 성상은 파편이 된 적혈구(schistocytes)가 말초혈액 도말 검사에 서 관찰되고 혈청 lactate dehydrogenase(LDH), 유리 혈색소와 망상 적혈구가 증가하며, 대개의 경우 혈소판 수치는 60,000/ mm 3 이하로 감소한다 1, 3) . 임상 증상과 예후...

Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy defined by the triad of sudden onset hemolytic anemia, thrombocytopenia, and acute kidney injury. We describe rare case atypical HUS secondary to pancreatitis with an unknown etiology in 20-year-old male who presented complaint nausea, vomiting, abdominal pain.

Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical hemolytic anemia, thrombocytopenia and renal impairment. Atypical HUS (aHUS) defines non Shiga-toxin-HUS and even if some authors include secondary aHUS due to Streptococcus pneumoniae or other causes, aHUS designates a primary disease due to a disorder in complement alternative pathway regulation. Atypical HUS represents 5 -...

HUS is one of the most common causes of acute renal failure in childhood. D+ HUS is the most common form and usually follows an episode of hemorrhagic colitis due to VTEC or S. dysenteriae type 1. The SLT elaborated by these organisms is responsible for the endothelial damage that is the initial insult in the pathogenesis of the acute renal failure. Excellent supportive care is necessary to red...