In order to elucidate the role of cortical input on sensory information processing in different thalamic somatosensory nuclei we recorded potentials evoked (EPs) by whisker deflections of short duration from ventral posteromedial (VPm) and medial posterior (POm) nuclei while manipulating cortico-thalamic activity by means of local cooling, lidocaine application or electrical stimulation. It app...

The changes in mean arterial pressure (MAP) and heart rate (HR) in response to the activation of metabotropic receptors in the nucleus tractus solitarii (NTS) with trans-(+/-)-1-amino-1,3-cyclopentanedicarboxylic acid (trans-(+/-)-ACPD) were evaluated in conscious and anesthetized Wistar, male rats weighing 240-260 g (N = 8). The responses obtained with trans-(+/-)-ACPD were compared with the r...

In the study, the possible effect of sodium valproate (NaVP) on urethane-induced lung tumors in mice has been evaluated. BALB/c mice (n = 120; 4-6 weeks old, both sexes) were used in the following groups: 1) urethane-treated, 2) urethane-NaVP-treated, 3) only NaVP-treated, 4) control. In the same groups, castrated male mice (n = 48) were investigated. Urethane was given by intraperitoneal injec...

Waterborne isocyanate-free grafted poly(hydroxy urethane)-poly(butyl methacrylate) hybrid dispersions were synthesized by miniemulsion polymerization. Grafting was induced including methacrylate functionalities in the urethane) and controlled degree of functionalization. It is shown that grafting enabled a fine tuning mechanical properties PHU containing hybrids.

Many investigators report recording from single units in the rodent visual pathway without neuromu~uIar relaxants to immobilize the eye. This is in contrast to the situation in the cat where it has been shown that neuromuscular blocking agents are required to reduce eye movements to a tolerable level (Cleland and Enroth-CugelI, 1966; Rod&k, Pettigrew, Nikara and Bishop, 1967). Attempts at contr...

This study investigated behavioral, anatomical and electrophysiological effects produced by electrical stimulation of posterior hypothalamic (PH) or median raphe (MR) nuclei, independently and during combined stimulation of both PH and MR. These three stimulation conditions were applied during spontaneous behavior in an open field and during PH stimulation-induced wheel running, while simultane...