نتایج جستجو برای: urinary glycosaminoglycans
تعداد نتایج: 112702 فیلتر نتایج به سال:
Chronic cystitis may be due to different known causes. Current basic science research has revealed a wide consensus that chronic cystitis may arise from a primary defective urothelium lining and in particular from a damage of its glycosaminoglycans (GAGs) component. The GAG layer is composed mainly of heparin, dermatan, the glycosaminoglycans, chondroitin sulphate (CS), and hyaluronic acid (HA)...
Several markers of renal changes have been measured in a cohort of 50 workers exposed to elemental mercury (Hg) and in 50 control workers. After application of selection criteria 44 exposed and 49 control workers were retained for the final statistical analysis. Exposed workers excreted on average 22 micrograms Hg/g creatinine and their mean duration of exposure was 11 years. Three types of ren...
OBJECTIVE To investigate the relationship between early-onset retinopathy and urinary markers of renal dysfunction. RESEARCH DESIGN AND METHODS The Diabetes Incidence Study in Sweden (DISS) aims to register all new cases of diabetes in young adults (15-34 years). In 1987-1988, 806 patients were reported and later invited to participate in a follow-up study focusing on microvascular complicati...
BACKGROUND The Steno hypothesis states that changes in basement membrane anionic charge leads to diabetic microvascular complications. In diabetic nephropathy, loss of basement membrane glycosaminoglycans and the association between glomerular basement membrane heparan sulphate and proteinuria has been documented. A correlation between erythrocyte surface and the glomerular capillary wall charg...
Analysis of urinary protein composition is an important tool in studies on renal physiology and physiopathology. Urine is, however, a complex mixture containing, besides protein, a variety of compounds such as salts, peptides, oligosaccharides, and glycosaminoglycans. Some of these compounds interfere with the electrophoretic migration of protein in sodium dodecyl sulfate-polyacrylamide gels an...
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