In this study, displacement field around v-notches of a poly methyl metha crylate (PMMA) specimen with tip cracks will be analyzed using digital image correlation technique. First intensity factor in combination with in-plane rigid body translations and rotation components will be determined by linear least squares fitting of the displacement field data to the corresponding relations among stre...

Th1 and Th17 are subsets of CD4 + T cells or T helper cells (Th). Th cells are the major adaptive immune cells involved in inflammation during the development of Multiple Sclerosis (MS). MS is a neurodegenerative autoimmune disease and one mouse model of the disease is Experimental Autoimmune Encephalomyelitis (EAE). Development and differentiation of Th1 and Th17 cells are regulated by the Not...

During Drosophila neurogenesis, glial differentiation depends on the expression of glial cells missing (gcm). Understanding how glial fate is achieved thus requires knowledge of the temporal and spatial control mechanisms directing gcm expression. A recent report showed that in the adult bristle lineage, gcm expression is negatively regulated by Notch signaling ( Van De Bor, V. and Giangrande, ...

The present study aimed to elucidate the role of Notch signaling in the development of myocardial infarction (MI) concomitant with diabetes in vivo and in vitro and evaluated the therapeutic effect of the Notch signaling in vitro. Streptozotocin-induced diabetic rats were subjected to 25 min of ischemia and 2 h of reperfusion. Cardiac troponin T (cTnT) and creatine kinase-MB (CK-MB) isoenzyme l...

The effect of V-notches or reentrant corners on fracture propagation has been analyzed for brittle materials, but not for quasibrittle materials such as concrete, marked by a large material characteristic length producing a strong size effect transitional between plasticity and linear elastic fracture mechanics. A simple size effect law for the nominal strength of quasibrittle structures with s...

Suprascapular nerve entrapment syndrome (SNES) is a neuropathy caused by compression of the nerve along its course. The most common compression sites include the suprascapular notch and the spinoglenoid notch. The aim of this article was to review the anatomical factors influencing the occurrence of SNES in the light of the newest reports. Potential predisposing morphological factors include a ...