Vulvo-vaginal candidiasis (VVC) is a common infection among women. 5-8% of women with acute infection experience recurrent vulvo-vaginal candidiasis (RVVC). There is currently no gold standard treatment for RVVC. Although antifungal agents such as imidazoles have been successfully used as first-line treatment for acute VVC, the effectiveness of these medications is limited for RVVC, and various...

OBJECTIVE To compare boric acid as an effective treatment for VVC compared to fluconazole. We also studied the efficiency of these drugs in preventing recurrence of VVC. DESIGN A cross sectional, randomized, double-blind study. SETTINGS Gynaecology clinic of Imam Reza hospital, Tehran - Iran SUBJECTS Women with signs and symptoms related to Vulvo Vaginal Candidiasis. RESULTS Seventy fiv...

OBJECTIVE To evaluate whether quantitative or qualitative IgA deficiencies in cervicovaginal secretions can be identified in patients with recurrent vulvovaginal candidiasis. DESIGN Prospective and controlled study. SETTING Department of Dermatology, University of Vienna. SUBJECTS 30 patients with symptomatic and recurrent vulvovaginal candidiasis at the time of their presentation. 30 hea...

Introduction : Vaginal candidiasis common problem among pregnant women. According to Jumbo G.T.A et al., during pregnancy women who did not know Candidiasis as a disease were 94.1% and 83.6% of the respondents felt there was no compelling need for treatment 1 while 86.3% did not consider the disease of any serious clinical significance . Objective : This study was conducted to find the effectiv...

A 32-year-old patient with chronic vaginal candidiasis was treated with 8 units of Transfer Factor (TF). Smears and cultures for Candida aZbicans became negative. Vaginal discharge and itching ceased, and the clinical condition of the vagina improved. Formerly negative delayed type skin tests with candidm converted to positive and Candida lymphocyte stimulation became measurable, suggesting tha...

Candidiasis is a yeast infection that is caused by a fungal microorganism, most often the fungus Candida albicans. Candidiasis is also known as thrush and can cause yeast infections in many areas of the body. These commonly include the mouth (oral thrush), the vagina (vaginal yeast infection, vaginal thrush) and the digestive tract (gastroenteritis) (Barnett, 2004). Infection of the mouth shows...

In order to analyse the relationship between intrauterine contraceptive device (IUCD) usage and Candida infection, we planned to examine cytologically the cervico-vaginal smears of 600 patients stained with Papanicolou method. Among 56 IUCD users 8 women had Candida infection (14%) while 44 of 544 non-users (8%) were infected by this fungus. Our detailed analyses indicated that the prolonged us...

In this metaanalysis of randomized controlled trials (RCTs) we aimed to compare the in vivo and in vitro activity and the safety of per os itraconazole and fluconazole treatment of uncomplicated acute vaginal/vulvovaginal candidiasis in nonpregnant women. We used PubMed, Scopus, Web of Science, and Cochrane Library to identify the studies that were relevant to our metaanalysis RCTs. Six RCTs we...

Women with recurrent vulvovaginal candidiasis often demonstrate a down-regulation of cell-mediated immunity (CMI) to Candida albicans detected by a lack of cutaneous delayed-type hypersensitivity (DTH) to Candida antigens. However, the role of systemic CMI as a host defense mechanism against recurrent vulvovaginal candidiasis is not well understood, in part because of the lack of a well-defined...