R adiation therapy has been a mainstay for treating lymphomas and can be curative in some lymphomas such as Hodgkin’s disease. Long term follow-up studies have shown progressive valvular heart disease in some patients, especially those with mediastinal radiation that includes the heart. In addition, these studies have observed that chemotherapy, particularly with anthracyclines, seemed to incre...

AIMS The cardiac valvular risk associated with lower exposure to cabergoline in common endocrine conditions such as hyperprolactinemia is unknown. METHODS AND RESULTS We performed a cross-sectional, case-control echocardiographic study to assess the valvular status in 102 subjects receiving cabergoline for endocrine disorders and 51 matched control subjects. Cabergoline treatment ranged from ...

SUCCESS in the surgical treatment of stenotic valvular disease of the heart has emphasized the urgency for the development of equally satisfactory methods for the correction of valvular insufficiencies. This need applies particularly to the mitral valve. Although mitral stenosis is quite common, it is relatively less so in the "pure" state. Bland stated that of 730 cases of rheumatic heart dise...

Regurgitation esophagitis is a constant and intractabe complication of the conventional esophagogastrostomy. A simple valvular and fundic formation was seen to abolish the distress''. No visual regurgitation was proved on the upper G.I. series as studied in 17 cases. Using a radioisotopic method, the present study was designed to demonstrate the absence of esophageal regurgitation among those p...

Mitral regurgitation (MR) is the second most common valvular heart disease in terms of prevalence and frequency indications for cardiac surgery. Severe MR characterized by a significant decrease exercise tolerance high mortality. The cause organic degenerative diseases. A detailed systematic assessment mitral valve mechanisms critical management these patients, planning type timing surgical int...

BACKGROUND Quadricuspid aortic valve is a rare congenital heart defect. Several different anatomical variations of a quadricuspid aortic valve has been described and aortic regurgitation is the predominant valvular dysfunction associated with quadricuspid aortic valve. CASE PRESENTATION A 68-year-old woman presented with almost a years history of increasing dyspnoea on exertion. The patient h...

Echocardiographic aspects of chronic mitral valvular disease were studied and compared to physical, radiographic and electrocardiographic aspects. Seventy dogs were used, and clinical examination, thoracic radiography, electrocardiogram and echocardiogram were performed. Correlations between regurgitation severity with cardiac failure functional class and murmur intensity were observed. The ele...

OBJECTIVES The goal of this study was to determine the prevalence of valvular regurgitation and abnormal valve morphology in patients three to five months after discontinuation of dexfenfluramine (Dexfen) therapy. BACKGROUND We previously reported the results of a randomized, double-blind, placebo-controlled trial of valvular structure and function in 1,073 patients treated either with Dexfen...

OBJECTIVES The purpose of this study was to describe the phenotypic characteristics of an inherited myxomatous valvular dystrophy mapped to Xq28. BACKGROUND Myxomatous valve dystrophies are a frequent cause of valvular diseases, the most common being idiopathic mitral valve prolapse. They form a group of heterogeneous diseases difficult to subclassify. The first mapping of the gene for a myxo...

Anaesthetic management of Caesarean section in a parturient with severe pulmonary stenosis and aortic regurgitation is described. The valvular sequelae resulted from previous unsuccessful surgical correction (Ross procedure) of congenital aortic stenosis. This case demonstrates the importance of multi-disciplinary assessment and careful anaesthetic planning, to avoid deterioration in perioperat...