background pyogenic bacteria and especially staphylococcus aurous (s. aurous) are the most common cause of chronic osteomyelitis. not only treatment protocol of chronic osteomyelitis occasionally is amiss but also this malady responds to treatment difficultly. objectives this study investigates antibiotic resistance pattern of s. aurous isolated from iranian patients who suffer from chronic ost...

conclusions regarding clinical and laboratory standards institute (clsi) definition for vancomycin susceptibility (mic < 2 μg/ml), it seems that vancomycin may not be considered as the best antibiotic in order to treat heteroresistant vancomycin intermediate s. aureus (hvisa) and vancomycin sensitive s. aureus (vssa) infections, and a new breakpoint for vancomycin and alternative antibiotics sh...

Increased prevalence of Vancomycin-resistant Enterococci and their ability to transfer Vancomycin resistance genes to other bacteria have made them a subject of close scrutiny and intense investigation. This study was performed to determine the prevalence of Vancomycin-resistant Enterococci occurrence in children hospitalized in a Hospital in Tehran, Iran. During 12 months, we collected 780 sto...

OBJECTIVE To assess the rate of faecal vancomycin-resistant Enterococcus colonisation in high-risk patients in a regional hospital. DESIGN Prospective observational surveillance study. SETTING Queen Elizabeth Hospital, Hong Kong. PATIENTS From September 2001 to December 2002, stool samples from patients in the intensive care unit and patients in whom Clostridium difficile testing was requ...

Background&Aims: Vancomycin Resistant Enterococci (VRE) are among the most common nosocomial pathogens worldwide. The intestinal tract provides a major source for transmission of these bacteria. Probiotics are living microorganisms that moderate use of them has inhibitory effect on intestinal colonization by enteric pathogens. We examined the effect of Lactobacillus rhamnosus GG (LGG) on inhibi...

Vancomycin is a glycopeptide antibiotic used for the treatment of Gram-positive bacterial infections. Traditionally, it has been used as a drug of last resort; however, clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA) strains with decreased susceptibility to vancomycin (vancomycin intermediate-resistant S. aureus [VISA]) and more recently with high-level vancomycin resist...

This study was undertaken to assess whether oropharyngeal vancomycin may control oropharyngeal carriage and lower airway infection due to methicillin-resistant Staphylococcus aureus (MRSA) acquired in the intensive care unit (ICU). Secondary endpoints were the emergence of vancomycin-resistant enterococci, vancomycin-intermediate S. aureus and vancomycin consumption. A total of 84 patients, adm...

Enterococci cause serious illness in immunocompromised patients and severely ill, hospitalized patients. Resistance to vancomycin has increased in frequency during the past few years. Limited therapeutic options are available for vancomycin-resistant enterococcal infections and the optimum therapy has not been established. We report a case of nosocomial vancomycin-resistant Enterococcus faecium...

The incidence of resistant gram-positive bacteria in nosocomial and, more recently, community-acquired infections is increasing. Staphylococci, because of their natural habitat on the skin, have always been the leading cause of peritonitis in patients receiving peritoneal dialysis (PD). These organisms have demonstrated a remarkable ability to develop resistance to antibiotics, first with penic...