The exact role of dopamine transporter gene (DAT1) in the pathogenesis of bipolar disorder type 1 (BD) is not understood. In the present study, we aimed to evaluate the possible association between 30, 40 and 63 bp variable number tandem repeat (VNTR) polymorphisms of DAT1 gene and the risk of type 1 (BD) in a sample of Iranian population. This case-control study was performed on 152 BD patient...

Phenylketonuria (PKU) is one of the most common known inherited metabolic diseases. The present study aimed to investigate the status of molecular defects in phenylalanine hydroxylase (PAH) gene in western Iranian PKU patients (predominantly from Kermanshah, Hamadan, and Lorestan provinces) during 2014-2016. Additionally, the results were compared with similar studies in Iran. Nucleotide sequen...

this study was designed to find out the impact of the variable number of tandem repeats (vntr) of the tumor necrosis factor receptor 2 (tnfrsf1b) on pulmonary tuberculosis (ptb) risk in an iranian population. this case-control study was done on 159 ptb patients and 158 healthy subjects. bi-allelic tnfrsf1b vntr was genotyped by polymerase chain reaction. logistic regression analysis revealed no...

in this paper, mixed convection of al2o3-eg-water nanofluid in a square lid-driven enclosure is investigated numerically. the focus of this study is on the effects of variable thermophysical properties of the nanofluid on the heat transfer characteristics. the top moving and the bottom stationary horizontal walls are insulated, while the vertical walls are kept at different constant temperature...

in this paper, the flow around bluff bodies with different cross sections and determination of forces acts on them are investigated.this paper presents the results of a numerical study on the flow characteristics and heat transfer over two equal square cylinders in a tandem arrangement. spacing between the cylinders is 5 widths of the cylinder and the reynolds number ranges from 1 to 200, pr=0....

BACKGROUND A defect of nitric oxide (NO) synthesis in the lung of high-altitude pulmonary edema (HAPE) has been suggested to contribute to its exaggerated pulmonary hypertension. Several polymorphisms have been identified in the gene encoding endothelial nitric oxide synthase (eNOS), which is a key enzyme responsible for NO synthesis, some of which were reported to be associated with vascular d...

in this paper, by using a new approach on distance between two fuzzy numbers, we construct a new ranking system for fuzzy number which is very realistic and also matching our intuition as the crisp ranking system on r.

aim: the aims of this study were to characterize iranian shigella sonnei strains isolated from pediatric cases and evaluate the utility of multilocus variable-number tandem-repeat (vntr) analysis (mlva) for genotyping of local s. sonnei strains. background: s. sonnei has become the dominant species in certain parts of iran. although pfge is still a gold standard for genotyping and source tracki...