adiponectin is one of the most important members of adipokine family which is widely synthesized and secreted by adipose tissue. the action of adiponectin is via binding to main receptors. it has several actions including regulation of glucose level, lipid homeo­stasis and reproductive system. adiponectin can also influence vascular endothelium via preventing the migration of monocytes. the rol...

Gotham's disease or vanishing bone is a rare disease with unknown etiology. Frequently, children and young adults are affected. It is characterized by proliferation of vascular or lymphatic tissue which results in destruction and resorption of bone. In this disease, the destructed bone is replaced either by hemangiomatous or lymphangiomatous tissue ( s) and in a later stage, fibrosis occurs. It...

Several methods have been developed for generating 3D, in vitro, organ-on-chip models of human vasculature to study vascular function, transport, and tissue engineering. However, many these existing lack...

The fields of vascular biology and vascular medicine are so intertwined that advances in one predict, explain, or are required for progress in the other. Bypass grafting, which once served as a “bailout” procedure,1,2 is now performed more than 600 000 times annually in the United States. In major part, this increase can be attributed to a surge in understanding of the vascular response to inju...

Tissue engineering of vascular grafts 187 1 3 Summary Background There is a considerable clinical need for a sufficient prosthetic small-diameter substitute which can compete with autologous vessels. Currently used synthetic materials have a poor performance due to high thrombogeneicity and development of intimal hyperplasia. Tissue engineering is an interesting alternative approach for vascula...

o bjective: to determine the etiology, signs and symptoms, angiography indications and angiography findings in patients with limb penetrating injuries suspected to have arterial injury. m e thods: this was a cross-sectional study being performed in imam reza hospital affiliated with mashhad university of medical sciences, iran between september 2011 and march 2013. we included those patients wi...