INTRODUCTION Leukocytoclastic vasculitis (also known as hypersensitivity vasculitis and cutaneous necrotizing vasculitis) can present with various manifestations, which often delays the diagnosis and treatment. In order to show the importance of the early recognition of leukocytoclastic vasculitis, we present a case which occurred secondary to the use of a common pharmaceutical, naproxen. We we...

BACKGROUND/AIMS Gastrointestinal involvement in vasculitis may result in life-threatening complications. However, its variable clinical presentations and endoscopic features, and the rarity of the disease, often result in delayed diagnosis. METHODS Clinical characteristics, endoscopic features, and histopathological findings were reviewed from medical records. RESULTS Of 6,477 patients with...

Immune complexes are found in the circulation of 30%-75% of patients with urticarial vasculitis and much evidence supports the role of these immune complexes in the pathogenesis of urticarial vasculitis. Plasmapheresis is effective for removing these immune complexes; however, there are few reports on the use of plasmapheresis in the treatment of urticarial vasculitis. We describe a case of "re...

Primary systemic vasculitides (PSV) in children belong to the most challenging conditions in paediatric rheumatology practice. The spectrum of vasculitis affecting children as well as their clinical presentations differ from that of adults. Apart from relatively common Henoch-Shönlein purpura and Kawasaki disease, chronic PSV are extremely rare in childhood. They include mainly childhood polyar...

Aim: Lymphocytic vasculitis is a morphological term which includes clinically heterogenous diseases like connective tissue disease, infection, lichenoid diseases, drug reaction, Behçet’s disease, superficial thrombophlebitis and leukemic vasculitis. There are three forms of lymphocytic vasculitis : angiodestructive form, lichenoid lymphocytic vasculitis and lymphocytic endovasculitis. There is ...

A genome analysis of mouse models may shed some light on the complex clinicopathological manifestations of systemic vasculitis. In the study of susceptibility loci to vasculitis in MRL mouse models, we found that systemic vasculitis developed through the cumulative effect of multiple gene loci, each of which by itself did not have a significant effect in inducing the related phenotype, thus ind...

kawasaki disease is a multi system disorder with varying clinical expressions. this disease is an acute systemic vasculitis of unknown etiology that has recently recognized as a leading cause of acquired heart disease in children of many developed countries. we describe an unusual instance of hair loss in a patient with kawasaki disease. a 26 months old boy developed prolonged high fever, bilat...

the association of takayasu arthritis (ta) and inflammatory bowel disease is rare. early diagnosis and treatment may influence patient survival. this report describes a 35-year-old woman who had been treated for ulcerative colitis (uc) that manifested with weight loss, upper limb cluadication and vertigo. the diagnosis of ta was made according to the american college of rheumatology criteria. t...

BACKGROUND Cutaneous vasculitis presents as a mosaic of clinical and histological findings. Its pathogenic mechanisms and clinical manifestations are varied. AIMS To study the epidemiological spectrum of cutaneous vasculitides as seen in a dermatologic clinic and to determine the clinico-pathological correlation. METHODS A cohort study was conducted on 50 consecutive patients clinically dia...

Vasculitis is defined as inflammation directed at vessels, which compromises or destroys the vessel wall leading to haemorrhagic and/or ischaemic events. Skin biopsy is the gold standard for the diagnosis of cutaneous vasculitis, whose manifestations include urticaria, infiltrative erythema, petechiae, purpura, purpuric papules, haemorrhagic vesicles and bullae, nodules, livedo racemosa, deep (...