نتایج جستجو برای: viremia

تعداد نتایج: 4845  

Journal: :The Journal of infectious diseases 2001
M F Para L A Kalish A C Collier E L Murphy W L Drew

The Viral Activation Transfusion Study compared leukocyte-reduced to unfiltered red blood cell transfusions in human immunodeficiency virus (HIV)- and cytomegalovirus (CMV)-coinfected patients. Relationships between serially measured plasma CMV load and clinical and laboratory outcomes over a median of 12 months were examined in 511 subjects. At baseline, subjects had a median of 15 CD4(+) cell...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2009
J B Dinoso S Y Kim A M Wiegand S E Palmer S J Gange L Cranmer A O'Shea M Callender A Spivak T Brennan M F Kearney M A Proschan J M Mican C A Rehm J M Coffin J W Mellors R F Siliciano F Maldarelli

In HIV-1-infected individuals on currently recommended antiretroviral therapy (ART), viremia is reduced to <50 copies of HIV-1 RNA per milliliter, but low-level residual viremia appears to persist over the lifetimes of most infected individuals. There is controversy over whether the residual viremia results from ongoing cycles of viral replication. To address this question, we conducted 2 prosp...

Journal: :Journal of Experimental Medicine 1954

2013
Zeenath U. Islam Stephen C. Bishop Nicholas J. Savill Raymond R. R. Rowland Joan K. Lunney Benjamin Trible Andrea B. Doeschl-Wilson

Porcine reproductive and respiratory syndrome (PRRS) is one of the most economically significant viral diseases facing the global swine industry. Viremia profiles of PRRS virus challenged pigs reflect the severity and progression of infection within the host and provide crucial information for subsequent control measures. In this study we analyse the largest longitudinal PRRS viremia dataset fr...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2013
Minh Nguyen Nguyet Thi Hue Kien Duong Vu Tuan Trung Than Ha Quyen Nguyen Chau N B Tran Vo Thi Long Le Thi Dui Hoa Lan Nguyen Jeremy J Farrar Edward C Holmes Maia A Rabaa Juliet E Bryant Truong Thanh Nguyen Huong Thi Cam Nguyen Lan Thi Hong Nguyen Mai Phuong Pham Hung The Nguyen Tai Thi Hue Luong Bridget Wills Chau Van Vinh Nguyen Marcel Wolbers Cameron P Simmons

Dengue is the most prevalent arboviral disease of humans. The host and virus variables associated with dengue virus (DENV) transmission from symptomatic dengue cases (n = 208) to Aedes aegypti mosquitoes during 407 independent exposure events was defined. The 50% mosquito infectious dose for each of DENV-1-4 ranged from 6.29 to 7.52 log10 RNA copies/mL of plasma. Increasing day of illness, decl...

Journal: :Pediatric Research 1977

Journal: :JAMA 2001
D V Havlir R Bassett D Levitan P Gilbert P Tebas A C Collier M S Hirsch C Ignacio J Condra H F Günthard D D Richman J K Wong

CONTEXT In HIV-infected patients having virologic suppression (plasma HIV RNA <50 copies/mL) with antiretroviral therapy, intermittent episodes of low-level viremia have been correlated with slower decay rates of latently infected cells and increased levels of viral evolution, but the clinical significance of these episodes is unknown. OBJECTIVE To determine if HIV-infected patients with inte...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2008
Sarah Palmer Frank Maldarelli Ann Wiegand Barry Bernstein George J Hanna Scott C Brun Dale J Kempf John W Mellors John M Coffin Martin S King

Residual viremia can be detected in most HIV-1-infected patients on antiretroviral therapy despite suppression of plasma RNA to <50 copies per ml, but the source and duration of this viremia is currently unknown. Therefore, we analyzed longitudinal plasma samples from 40 patients enrolled in the Abbott M97-720 trial at baseline (pretherapy) and weeks 60 to 384 by using an HIV-1 RNA assay with s...

Journal: :The Journal of infectious diseases 2011
Judson Heugel Michael Boeckh Meei-Li Huang Becky Dierks Robert Hackman David Fredricks Jane Kuypers Lawrence Corey

Adeno-associated virus (AAV) is widely considered to be nonpathogenic, but the clinical epidemiology of this virus is limited. By use of polymerase chain reaction assays, we investigated the incidence and clinical significance of AAV viremia in a population of consecutive recipients of a hematopoietic cell transplant (HCT). Four (2.8%) of 145 patients developed AAV viremia after HCT. Viremia wa...

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