Background. Traditional mistletoe therapy in cancer patients involves subcutaneous applications of Viscum album L. preparations, with doses slowly increasing based on patient responses. Intravenous infusion of high doses may improve therapeutic outcomes and is becoming more common. Little is known about the safety of this "off-label" application of mistletoe. Methods. An observational study was...

1. The haemagglutinating and toxic lectin from Viscum album L. (mistletoe) inhibits protein synthesis in a lysate of rabbit reticulocytes, with an ID50 (concentration giving 50% inhibition) of 2.6 microgram/ml. This effect is enhanced (ID50 0.21 microgram/ml) if the lectin is reduced with 2-mercaptoethanol. 2. The lectin inhibits protein synthesis also in BL8L cells in culture. Inhibition occur...

Mistletoe has been used as a drug against different diseases in po­ pular medicine for a long time, but the systematic research into anti-neoplastic activity of mistletoe extracts started only recently. Biological and anti-tumor activity of many protein fractions from mistletoe ex­ tract has been thouroughly investigated by V e s t e r et al. (1968 a, b), who determined optimal conditions for t...

BACKGROUND Mistletoe (Viscum album L.) extracts are widely used in complementary cancer therapy. Aim of this study was to evaluate safety and efficacy of a standardized mistletoe extract (abnobaVISCUM(®) Quercus, aVQ) in patients with gastric cancer. PATIENTS AND METHODS 32 operated gastric cancer patients (stage Ib or II) who were waiting for oral chemotherapy with the 5-FU prodrug doxifluri...

Viscum album leaf extract has a folk reputation as an antihypertensive agent in Nigeria. Evidence suggests that it has a relaxant effect on smooth muscle. The present study was designed to investigate the role of calcium in the vasorelaxant effect of this extract. Concentration response studies to noradrenaline, KCl and CaCl2 were carried out in rat aortic rings with and without the extract in ...

extracts derived from viscum album have been shown to kill cancer cells in vitro. some studies have noted that different species of this plant collected from around the world displayed cytotoxic effects in different extents. in the present study, we evaluated the effects of iranian mistletoe extracts on five cancer cell lines. plants growing on hornbeam tree (carpinus betulus) were collected, a...

Plants are rich sources of antioxidant compounds including phenols and flavonoids. These antioxidants crucial elements in diet protect the body against oxidative stress. In this study, activity phenolic flavonoids mistletoe (Viscum album), as a substituent for synthetic antioxidants, was quantitatively investigated. The plant alcoholic (ethanol) extract used biosynthesis ZnO/SnO2 composite nano...

objective: the present study was designed to investigate the analgesic effect of oral and i.p. administration of alcoholic viscum album (v.a) fruit extract as a rich source of alkaloid substances. materials and methods: experimented animals were divided into control and treatment groups. the treatment rats received different doses of the v.a fruit extract, which was prepared from alcoholic sma...

Despite a long tradition of use in the treatment of mental disorders, Viscum album L. (Ujjral; family – Viscaceae) has not been systematically investigated to validate its traditional claims. The methanol extract of V. album aerial parts, its ethyl acetate fraction (EAF) and 1-butanol fraction (BF) were screened for various neuropharmacological activities. The methanol extract, EAF and BF exhib...