objective(s) there is well documented evidence for the increase in widespread use of complementary and alternative medicine in the treatment of physical and psychiatric symptoms and disorders within the populations. in the present study, we investigated the influence of vitex agnus-castus (vitex) on anxiety-like behaviors of rats. materials and methods elevated plus maze which is one of the met...

Background: Phytoestrogens are some plant compounds with estrogenic biological effects which are found in many nutritional sources as soybean, flaxseed, and sesame. Vitex agnus-castus, also called Vitex, owns  phytoestrogen properties. Studies have shown that phytoestrogens have different impacts on the gestation process and reproduction indices. Objective: The present study was aimed to inves...

  Background: Vitex agnus - castus extract (Vitex) is available in dosage forms for female disorders treatment. This extract has shown controversial effects against seizures induced by Maximal electroshock (MES) or pentylenetetrazole (PTZ).   Objective: In the present study the anti-seizure activity of Vitex against acquisition of amygdala kindling was evaluated in male rats.   Methods: Intact ...

Local medicinal plants from Madina, Saudi Arabia, are used to cure various diseases. However, some can cause adverse health effects. Five different medicinal plants were collected in the city of Madina: mahareeb (Cymbopogon), sheeh (Artemisia), harjal (Cynanchum argel delile), nabipoot (Equisetum), and kafmariam (Vitex agnus-castus). In total, four toxic elements including Al, Pb, As, and Cd we...

vitex agnus-castus l. is a medicinal plant which is used in several dosage forms for women hormonal disorders and standardized according to the iridoids or flavonoids content. aucubin, an iridoid glycoside, considered as a marker in some formulations. in this research, a thin layer chromatographic method with densitometric detection has been developed for quantitative determination of aucubin i...

introduction: lower level of estrogen hormone is considered as an important factor for loss of learning and memory in postmenopausal women. although estrogen replacement therapy is used for compensation, but long-term usage of estrogen is associated with a higher risk of hormonedependent cancers. phytoestrogens, due to fewer side effects, have been proposed to prevent menopause-related cognitiv...