نتایج جستجو برای: vsx1

تعداد نتایج: 79  

Journal: :Reproductive system & sexual disorders : current research 2012
Joshua Wheeler Michael A Hauser Natalie A Afshari R Rand Allingham Yutao Liu

Keratoconus is the most common ectatic disorder of the corneal. Genetic and environmental factors may contribute to its pathogenesis. The focus of this article is to summarize current research into the complex genetics of keratoconus. We discuss the evidence of genetic etiology including family-based linkage studies, twin studies, genetic mutations, and genome-wide association studies. The gene...

2009
Vanessa Barbaro Stefano Ferrari Adriano Fasolo Diego Ponzin Enzo Di Iorio

PURPOSE To reconstruct a human hemicornea in vitro by means of limbal stem cells cultured onto human keratoplasty lenticules (HKLs) and to obtain a natural corneal graft for clinical applications. METHODS Limbal stem cells were seeded onto HKLs with or without the presence of feeder layers of lethally irradiated 3T3-J2 cells and compared with the current "gold standard" scaffold, i.e., the fi...

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