In 1931 Klinger published a case of nasal sinusitis which terminated in renal failure. There have since been a number of reports of a syndrome characterized clinically by a combination of intractable rhinitis or pulmonary symptoms, manifestat.ons of polyarteritis nodosa, and renal failure. Pathologically, the disease is recognized by the association of necrotizing granulomata of the respiratory...

Simpson's long working life covered a wide field. The pioneering nature of his work in public health and tropical hygiene involved a number of appointments at home and abroad. He worked in Aberdeen as Medical Officer of Health, in India as Health Officer for Calcutta, and in London he taught as Professor of Hygiene at King's College, becoming one of the founders of the London School of Hygiene ...

Defects in the pars interarticularis are rarely present at birth, and seldom appear clinically before the age at which a child can stand upright. The incidence then increases up to the third or fourth decade (Rowe and Roche 1953, Stewart 1953). In radiological surveys of normal industrial and military populations, spondylolysis has been reported in up to 76 per cent (Friedman, Fischer and van D...