This study aimed to assess whether night shift work is associated with the risk of depression by using a meta-analysis of observational studies. We searched PubMed and EMBASE in August, 2016 to locate eligible studies and investigated the association between night shift work and the risk of depression, reporting outcome measures with adjusted odds ratios (ORs) or relative risks (RRs) and 95% co...

To resolve tensions among competing sources of evidence and public expectations, health-care managers and policy makers are turning more than ever to involve the public in a wide range of decisions. Yet efforts to use research evidence to inform public involvement decisions are hampered by an absence of rigorous public participation evaluation research. In particular, greater rigour in explorin...

This review summarizes recent evidence that prenatal exposure to diverse environmental chemicals dysregulates the fetal epigenome, with potential consequences for subsequent developmental disorders and disease manifesting in childhood, over the lifecourse, or even transgenerationally. The primordial germ cells, embryo, and fetus are highly susceptible to epigenetic dysregulation by environmenta...

Shade avoidance is an ecologically and molecularly well-understood set of plant developmental responses that occur when the ratio of red to far-red light (R:FR) is reduced as a result of foliar shade. Here, a genome-wide association study (GWAS) in Arabidopsis thaliana was used to identify variants underlying one of these responses: increased hypocotyl elongation. Four hypocotyl phenotypes were...

Aberrant methylation of CpG islands (CpG-rich regions of DNA associated with the promoters of many genes) is associated with transcriptional inactivation of genes involved in tumour development. Genes involved in key DNA damage response pathways, such as cell-cycle control, apoptosis signalling and DNA repair can frequently become epigenetically silenced and methylated in tumours. This may lead...

Social experiences occurring during infancy have been demonstrated to exert persistent effects on neurobiological and behavioral outcomes. This social modulation of the developing brain has been observed in humans and animal models of abuse, neglect, and variation in parental style. Although the mechanisms through which these effects are achieved likely involve diverse cellular and molecular pa...

Work Engagement and Innovative Behavior: Meta-Analysis Study Devietha Kurnia Sari1,*, Ananta Yudiarso2, Frikson Christian Sinambela3 1 Department of Master Science in Psychology, Faculty UBAYA, Surabaya, Indonesia 2, 3 *Corresponding author. Email: [email protected] ABSTRACT is referred to as the motivation employees have involving being enthusiastic about their work. An engaged em...

The novel discipline of nutriepigenomics integrates knowledge on nutrigenomics and the reciprocal effects that epigenetic changes exert on gene expression under the influence of nutritional factors. Mutual interactions among genes, nutrients and nutrition-induced epigenetic modifications configure the nutriepigenomic outcome. This trinomial interaction is highly complex and this field is still ...