Objective-This study was conducted to evaluate the effect of co-administration of Aloe vera gel and cinnamon zeynalicum bark hydroethanolic extract on process of wound healing in diabetic mice model.Design- Experimental Study.Animals- Seventy-two male BALB/c mice.Procedures- A single full-thickness excisional wound was created on ba...

background : bacterial infections in burn and wound patients are common and difficult to control. the aim of the current study was to evaluate the ability of full length oprf to elicit the production of protective igg in mice burn wound sepsis model against p. aeruginosa infection. methods : oprf protein was expressed and purified by ni-nta. the purified protein as used to immunize balb/c mice....

Propolis is a resinous, sticky substance that bees collect from conifer buds and use to repair cracks in their hives. Propolis was used in folk medicine as early as 300 BC as an anti-inflammatory drug and wound healing agent. We studied the effect of Propolis on wound healing in albino rats. Twenty male albino rats had a linear 3 cm incision made over skin of back. The animals were randomly div...

An in vitro study on the role of intracellular calcium ions in healing of excisional wound in rabbit was undertaken. We employed two drugs namely, glibenclamide and nitroglycerin that are topically applied in vivo to modulate the activity of intracellular calcium. Our model consisted of a 15 ´ 15 mm excisional wound. Seven groups of New Zealand rabbits were used. The first three groups served a...

Background and Objective: Skin ulcers and their slow healing are considered as one of the important medical aspects. Nowadays, various antibiotics and materials are used to accelerate the wound healing process. One of the methods taken in the field of wound healing is using ozone. On the other hand, one of the factors that hurt the speed of wound healing is stress. Therefore, the present study ...

this research established the scientific bases for the folkloric use of the neglected dialium guineense fruit coat in wound and microbial infection management in nigeria. the phytochemical analysis of the crude extract, fractions and sub-fractions was performed by standard methods. agar well diffusion protocol was adopted for the antimicrobial assay while the wound healing properties was determ...

Background: 2,3-dimethylquinoxaline (DMQ) is a naturally occurring compound with documented antifungal activity. It showed also good in vitro physicochemical and pharmacokinetic characteristics.
 Methods: The wound healing activity of 1% DMQ hydrogel healthy adult male Wister rats were evaluated using the excision model. On day 7, mean percentage closure area was determined. animals sacrif...

BACKGROUND The paste of stem bark of Azadirachta indica (AI) has been traditionally used on wound and scar for rapid healing in Bundelkhand region of India. OBJECTIVE In the present investigation, wound healing potential of different extracts of stem bark of AI was explored in mice model. MATERIALS AND METHODS To study the wound healing properties in small animal model, the excision and inc...

exogenous nitric oxide donors such as deta nonoate, spontaneously release nitric oxide. this study aimed to investigate the effect of deta nonoate as a nitric oxide releasing drug on the rate of collagen synthesis during the impaired wound healing in a rat model of diabetes. twelve male sprague–dawley rats were transferred into separate metabolic cages. nine days before wounding, the rats were ...