نتایج جستجو برای: xeloda
تعداد نتایج: 238 فیلتر نتایج به سال:
BACKGROUND Capecitabine (Xeloda) is a fluoropyrimidine which is transformed to 5-fluorouracil (5-FU) at the tumor site. The aim of the present study was to estimate the efficacy of this agent in pretreated patients with advanced breast and colorectal cancer, and to determine the response rate and adverse reactions. PATIENTS AND METHODS Forty-two patients (median age 65 years, range 27-80 year...
PURPOSE The purpose of this study was to evaluate the efficacy and toxicity of a third-generation chemotherapy regimen in the adjuvant setting to radically operated patients with gastric cancer. This proposed new adjuvant regimen was also compared with a consecutive retrospective cohort of patients treated with the classic McDonald regimen. METHODS Starting in 2006, a non-randomized prospecti...
Abstract Background ?-catenin is an important unit of the Wnt/?-catenin signaling pathway, a conserved process involving several physiological activities, encompassing differentiation and cell proliferation, etc. The dysfunction or mutation in causing initiation advancement various neoplasm types, including colorectal cancer, breast etc., has been reported. Therefore, therapeutic target. Hence,...
BACKGROUND Capecitabine plus oxaliplatin (XELOX) has been established as a first-line treatment for metastatic colorectal cancer. Adherence is particularly important with capecitabine to maintain appropriate curative effect. In this study, we monitored the adherence to capecitabine on XELOX treatment and investigated which factors might decrease compliance. METHODS The study included 242 cons...
Target therapy in metastatic colorectal cancer needs the determination of KRAS, NRAS, and BRAF mutation status to identify patients resistant anti-EGFR treatment. RASgenes (KRAS+NRAS) are mutated 40-50% 5-10%; presence a double RAS is very rare phenomenon, which why mutations considered exclusive each other. Herein, we describe novel concomitant NRAS/BRAF series patients. A 800 carcinomas fixed...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید