The aim of this study was to investigate the impact general anesthetic drug ketamine and premedication agents medetomidine xylazine, their reversal by atipamezole, on monitored anesthesia care values ocular parameters such as intraocular pressure, horizontal pupillar diameter, Schirmer tear test in cats. A randomized, single-blinded conducted. Twenty intact female cats (weiging between 2.2 3.6 ...

The aim of the present study was to determine the effect of ketamine/ xylazine and pentobarbital anaesthesia on heart rate variability as a marker of autonomic nervous system activity. The experiments were performed in ketamine/ xylazine (10 mg/kg/15 mg/kg) and pentobarbital (40 mg/kg, i.p.) anaesthetized female Wistar rats, after adaptation to a light-dark cycle of 12 hours light: 12 hours dar...

Xylazine hydrochloride, α2 adrenoceptor agonist, is an analgesic, sedative, tranquilizer, and muscle relaxant agent in veterinary medicine which is mostly used as in pre-anesthesia in veterinary medicine. One of the main adverse effects of xylazine which limits application of this medication in small animal veterinary practice (mostly in cats) is nausea and vomiting which can end up with aspira...

the aim of this study was to determine whether anesthesia consisting of sedation induced by intramuscular administration of xylazine-diazepam and lumbosacral analgesia induced by epidural administration of lidocaine and xylazine is satisfactory for castration and ovariohysterectomy in cats. six adult (3 male and 3 female, 2.5 ± 0.5 years of age) cats (mean body weight ± sd, 2.2 ± 0.44 kg) were ...

Objectives: To evaluate if epidural administration of xylazine could decrease the effective dose of intravenous ketamine for maintenance of general anesthesia in laparoscopic procedures and assessment of related complications during anesthesia. Design: Experimental Study. Animals: 20 Female dogs with 21.0 ± 3.0 kg weight and 18.0 ± 1.2 months age. Material and methods: Animals randomly divid...

Thirty two free-ranging female white-tailed deer (Odocoileus virginianus) were anesthesized with varying Telazol and xylazine HCl combinations in Front Royal (Virginia, USA) between August 1992 and September 1992. All animals were caught in baited box traps, manually restrained, and hand injected with a combination of Telazol and xylazine administered intramuscularly. Deer received mean +/- SE ...

Ketamine, an NMDA receptor antagonist, is commonly used in combination with xylazine, an alpha 2-adrenergic receptor agonist, to induce surgical anesthesia in birds and other vertebrates. Problems associated with this anesthetic combination include impaired thermoregulation, compounded by the inability to feed while anesthesia lasts (approximately 6 h after a single dose), and the ketamine-indu...