a topical o/w cream containing tretinoin microspheres was prepared. gelatin microspheres of tretinoin were prepared using coacervation method. these microspheres contained about 50% w/w tretinoin. the particle size range of microspheres was between 90-150 m m. in vitro drug release from microspheres and a cream formulation was studied. it was shown that drug release from microspheres followed h...

We show global and interior higher-order log-Hölder regularity estimates for solutions of Dirichlet integral equations where the operator has a nonintegrable kernel with singularity at origin that is weaker than any fractional Laplacian. As consequence, under mild assumptions on right hand side, we existence classical problems involving logarithmic Laplacian Schrödinger operator.