نتایج جستجو برای: zinc database
تعداد نتایج: 340630 فیلتر نتایج به سال:
Database outsourcing is an idea to eliminate the burden of database management from organizations. Since data is a critical asset of organizations, preserving its privacy from outside adversary and untrusted server should be warranted. In this paper, we present a distributed scheme based on storing shares of data on different servers and separating indexes from data on a distinct server. Shamir...
Zinc-finger nucleases (ZFNs) allow targeted gene inactivation in a wide range of model organisms. However, construction of target-specific ZFNs is technically challenging. Here, we evaluate a straightforward modular assembly-based approach for ZFN construction and gene inactivation in zebrafish. From an archive of 27 different zinc-finger modules, we assembled more than 70 different zinc-finger...
this study was carried out in order to develop a soil fertility database and to assess agricultural soil fertility of country. to this end, 315000 soil test data (more than 50000 soil samples) that provided by laboratories of soil and water research centers in 30 provinces of iran between 2002 and 2012 was collected. results revealed that amount of plant available phosphorus and potassium of ...
SSO2064 is the first structural representative of PF01796 (DUF35), a large prokaryotic family with a wide phylogenetic distribution. The structure reveals a novel two-domain architecture comprising an N-terminal, rubredoxin-like, zinc ribbon and a C-terminal, oligonucleotide/oligosaccharide-binding (OB) fold domain. Additional N-terminal helical segments may be involved in protein-protein inter...
The three dimensional structure of Aedes aegypti chorion peroxidase was computed by homology modeling. The ModWeb server provided the most accurate model with QMEAN score of 0.642. The protein model consists of 36.1% alpha-helices and 1% beta-strand. Ligand binding sites in Aedes aegypti chorion peroxidase were identified using SiteComp server. In silico docking of a subset of ZINC natural prod...
Hepatitis C Virus (HCV) infection is a serious cause of chronic liver disease worldwide with more than 170 million infected individuals at a risk of developing significant morbidity and mortality. There is no effective treatment or prevention till date for HCV infection. We describe the computed binding of 10 compounds to the allosteric binding site of RNA dependent RNA polymerase enzyme. These...
Capillary electrophoresis/time-of-flight mass spectrometry(CE/TOFMS) has been used for analysis of in-gel digests of protein spots excised from two-dimensional sodium dodecyl sulfate polyacrylamide gel electrophoresis (2-D SDS-PAGE). An off-line purification and preconcentration procedure with a Zip Tip is used before CE/TOFMS analysis which allows for detection of protein spots with <1 picomol...
background bladder reconstruction in the pediatric population is challenging for many reasons, including perioperative complications and readmissions. objectives on a national scale, determine readmission rates at 30, 60 and 90 days after bladder reconstruction in a pediatric population over a 7-year period, evaluating the influence of hospital and patient-specific variables. patients and metho...
Wnts are the major ligands responsible for activating Wnt signaling pathway through binding to Frizzled proteins (Fzd) as the receptors. Among these ligands, Wnt2 plays the main role in the tumorigenesis of several human cancers especially colorectal cancer (CRC). Therefore, it can be considered as a potential drug target.The aim of this study was to identify potential drug candidates ...
Wnts are the major ligands responsible for activating Wnt signaling pathway through binding to Frizzled proteins (Fzd) as the receptors. Among these ligands, Wnt2 plays the main role in the tumorigenesis of several human cancers especially colorectal cancer (CRC). Therefore, it can be considered as a potential drug target.The aim of this study was to identify potential drug candidates ...
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