Numerous attempts have been made to control leptospirosis by using chemoprophylaxis, but with limited success. The present study was done investigate the antileptospiral potential of hexane, ethyl acetate and methanol extracts Zingiber zerumbet rhizomes. were assayed for activity broth microdilution method against Leptospira interrogans (serovar Batavie, Canicola, Australis) biflexa serovar Pat...

Zerumbone (ZER), a natural compound has been extracted from Zingiber zerumbet with known pharmacological activities. The aim was to determine the anti-human Burkitt’s lymphoma (Raji) cell effect of ZER. 3-(4,5-dimethylthiazol-2-yl)-2,5,-diphenyltetrazolium bromide (MTT) assay used cytotoxic while Annexin-V-fluorescein isothiocyanate/propidium iodide-PI flow cytometric assays apoptotic ZER on hu...