A previous report from this laboratory (van Golde, L.M.G., Schulman, H., and Kennedy, E.P. (1973) Proc. Natl. Acad. Sci. U.S.A. 70, 1368-1372) described the discovery in Escherichia coli of a novel class of oligosaccharides, containing glucose as the sole sugar, substituted with glycerophosphate units derived from membrane phospholipids, and with succinic acid in O-ester linkage. These membrane...

A histochemical study was made of a-glycerophosphate dehydrogenase in human tumors of @30cases. Enzymatic activity was generally confined to the cell plasma in neoplastic cells, and stromal reaction was usually low or absent. The stainability for a-glycerophosphate dehydrogenase was constant in normal tissue, whereas that of neo plastic cells was variable. Squamous-cell carcinomas showed varyin...

In 1938-9 at the British Postgraduate Medical School, King & Aloisi isolated from dried pancreas a glycerophosphoric ester of choline which was found to be readily hydrolyzable. Evidence was also obtained for the existence of a dicholine ester. This work was published only in 1945 owing to war difficulties. In the same year Schmidt, Hershman & Thanmhauser (1945) reported the isolation of aglyce...

Jackson, Robert W. (Purdue University, Lafayette, Ind.), and Merwin Moskowitz. Nature of a red cell sensitizing substance from streptococci. J. Bacteriol. 91:2205-2209. 1966.-A method for purifying a streptococcal antigen which sensitizes red cells to agglutination by antiserum is described. The antigen, when purified by this method, is almost exclusively composed of glycerophosphate and d-alan...

BACKGROUND: this study was designed to characterize some of the biochemical and molecular genetic changes during reversion of human fat cells. METHODS: mature adipocytes were isolated from greater omental fat tissue of eight lean and 14 massively obese persons by established methodology. RESULTS: at day 7 of adherence to Leighton tubes, there was appreciable depletion of triacylglycerol, as wel...