Study objective: to determine the role and effectiveness of proposed therapeutic preventive complex psychoemotional correction hormonal disorders in pregnancy dynamics after assisted reproductive technologies (ART) improve antenatal observation prevention obstetric perinatal complications.Materials methods. The study included 299 pregnant women: main group 249 women whose occurred as an ART res...

Objective. To investigate serum levels of free β-HCG, progesterone, and ischemia-modified albumin (IMA) and their combined use in the prediction of first trimester abortions. Methods. A total of 156 pregnant women between 5 and 13 weeks of gestational age were included in this study. At admission, serum levels of free β-HCG, progesterone, and IMA were noted and all cases were divided into two g...

Abbreviations: HCG: Human Chorionic Gonadotropin; Β-hCG: Β-Human Chorionic Gonadotropin; DVT: Deep Vein Thrombosis; TMP-SMX: Trimethoprim and Sulfamethoxazole; EBV: Epstein Barr Virus; ALT: Alanine Aminotransferase; AST: Aspartate Aminotransferase; ALP: Alkaline Phosphatase, PT: Prothrombin Time; CBC: Complete Blood Cell; AFLP: Acute Fatty Liver of Pregnancy; DKA: Diabetic Ketoacidosis; GTD: Ge...

Due to their extensive structural heterogeneity, the elucidation of glycosylation patterns in glycoproteins such as the subunits of human chorionic gonadotropin (hCG), hCG-α and hCG-β remains one of the most challenging problems in the proteomic analysis of posttranslational modifications. In consequence, glycosylation is usually studied after decomposition of the intact proteins to the proteo...

BACKGROUND Nowadays, The first step in treatment of ectopic pregnancy (EP) is medical treatment. Medical treatment with methotrexate (MTX) for EP is safe and effective method without the risks associated with the surgical procedure. But there are controversies between studies for which patients will respond better to medical treatment. OBJECTIVE The aim of the present study was to investigate...

Objective. To evaluate trophoblastic cell proliferation and angiogenesis in tubal pregnancy assessed by immunohistochemical study and their correlation with an average variation of β -hCG in an interval of 48 hours before surgery. Methods. A prospective study was conducted on 18 patients with a diagnosis of tubal pregnancy. The patients were divided into two groups of ectopic pregnancy of which...

We describe a case of choriocarcinoma with multiple organ metastases after term delivery. A 43-year-old female was diagnosed as choriocarcinoma with metastases to the liver, lungs, marrow cavity, thoracic vertebra and brain, based on serum levels of β-human chorionic gonadotrophin (β-hCG), clinical symptoms, gynecological examination, PET/CT examination and medical histories. Fourteen courses o...

OBJECTIVE To identify whether cutoff for sensitivity advertised by three pregnancy tests in urine are compatible to those reported by the manufacturer and to describe their diagnostic performance. METHODS The urine of a male volunteer was used to dilute recombinant β-hCG at defined concentrations of 0, 6.25, 12.5, 25, 50, and 100 mIU/mL. The tubes containing each of the concentrations were co...