نتایج جستجو برای: γ r1 ifn
تعداد نتایج: 106906 فیلتر نتایج به سال:
Background: Brucella is a gram-negative bacterium, causing acute and chronic infection in humans and animals. Cell-mediated immunity is the main protective immune response against Brucella spp. Activation of macrophages by IFN-γ and generation of reactive oxygen intermediates and nitric oxide are the main immunologic mechanisms responsible for control of Brucella infection. Objective: To invest...
The aim of this study was to investigate the immunomodulatory effects of Spirulina platensis (S.platensis) by measuring the levels of serum interleukin (IL)-4, IL-10, IL-17, tumor necrosis factor(TNF)-α and interferon (IFN)-|γ| in mice suffered from systemic candidiasis and breast cancer. Theaqueous extract of S. platensis was selected for this study. Balb/C female mice were inoculated withCand...
تفاوتهای ژنتیکی (میزبان و ویروس) و ایمونولوژیکی سهم عمده ای در عدم توانایی سیستم ایمنی در پاکسازی کامل ویروس در بیماران مبتلا به عفونت نهفته هپاتیت b obi دارند. ما در این مطالعه به بررسی برخی ویژگیهای ویروس آلوده کننده و تعدادی از فاکتورهای ایمونولوژیکی بیماران مبتلا به obi و مقایسه آن با افراد سالم پرداختیم. 3700 عدد پلاسمای hbsag منفی از نظر anti-hbc مورد بررسی قرار گرفتند سپس نمونه های hbsag...
Abstract Background and objectives: Interferon-Gamma and interferon Gamma receptor (IFNγ ⁄ IFNγR1) are the main genes associated with susceptibility to tuberculosis. We aimed at studying on interferon-Gamma Gene polymorphism(- 56 C/T) in people suffered from tuberculosis (TB). Material and Methods: In this case-control study, the subjects were 62 individuals with TB and 74 hea...
Background: Atopic dermatitis (AD) is one of the most common chronic, highly pruritic and inflammatory skin diseases. The exclusive influence of breastfeeding in the prevention of inflammatory diseases is a matter of debate. In this study, we aimed to determine the concentration of interferon-gamma (IFN-γ), tumor necrosis factor-alpha (TNF-α), interleukin-13 (IL-13) and interleukin-4 (IL-4) cyt...
چکیده زمینه و هدف: انگل های لیشمانیا، در صورت فعال شدن ماکروفاژها قابل فاگوسیت شدن می باشند، این سازوکار با تولید رادیکال های فعال اکسیژن و نیتریک اکساید قابل انجام است، که از طریق ایمونومدولاتور ها صورت می گیرد. دراین مطالعه، تأثیر عصاره آبی سیر بر سلول های j774 آلوده به انگل لیشمانیا ماژور و بیان ژن های inos و ifn γ مورد بررسی قرار گرفته است. مواد و روش ها: در این مطالعه آزمایشگاهی سلول ه...
BACKGROUND: Interleukin-4 (IL-4) is a cytokine of Th2 response and plays role as reducer or silencer Th1 work. It more related to allergic processes, with consequent loss control the disease (i.e., tuberculosis). Interferon gamma (IFN-γ) Type II interferon that inhibits immune inducts inhibit tuberculous viral replication, any immunostimulatory immunomodulatory effects. Dark specks (DS) are in ...
BACKGROUND Treatment of HBV chronic carriers using interferon (IFN)-α or nucleoside/nucleotide analogues fails to suppress viral infection. Type-II IFN-γ has been shown to inhibit HBV replication. The goal of the present work was to evaluate the antiviral efficacy against HBV of a thermostable IFN-γ variant isolated using Massive Mutagenesis and thermoresistant selection (THR) technologies. M...
IFN-γ Receptor-Ligand Binding. IFN-γ binds to receptors on the macrophage surface, initiating a cascade of events leading to an increase in MHC class II expression (1). We assume that this increase is the primary mechanism by which IFN-γ facilitates antigen presentation. To represent IFN-γ receptor-ligand binding, we use the general reaction scheme ligand + receptor ↔ complex. Other processes a...
objective: in this study, we sought to better understand the immunoregulatory function of stem cells derived from human exfoliated deciduous teeth (shed). we studied the role of the interferon gamma (ifn-γ)-indoleamine 2,3-dioxygenase (ido)-axis in immunoregulation of shed compared to bone marrow derived mesenchymal stem cells (bmmscs) under the same conditions. materials and methods: in this c...
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