The glycerol dehydration test (GDT) has been used to test for the presence of Ménière's disease and elicits acute alterations in vestibular reflexes in both normal and pathological states. Activation of the vestibulosympathetic reflex (VSR) increases muscle sympathetic nerve activity (MSNA) and peripheral vascular resistance. We hypothesized that the GDT would attenuate the VSR through fluid sh...

Testosterone (TES) and other androgens exert a direct vasorelaxing action on the vasculature in vitro that is structurally specific and independent of cytosolic androgen receptor (AR). The effects of intravenous androgen infusions on mean arterial blood pressure (BP) and heart rate (HR) were determined in conscious, unrestrained, chronically catheterized, ganglionically blocked (hexamethonium, ...

The nature of the Cenomanian–Turonian Oceanic Anoxic Event (CTOAE) and its δ13 C Excursion is considered in light (1) stratigraphical framework which CTOAE developed European shelf seas, (2) conclusions that can be drawn from new detailed investigations Chalk succession at three locations England, Melton Ross Flixton Northern Province where organic-rich ‘black bands’ are present, Dover Southern...

This study investigates the contribution of different CH4 sources to seasonal cycle δ13C during 2000–2012 by using TM5 atmospheric transport model, including spatially varying information on isotopic signatures. The model is able produce background seasonality δ13C, but discrepancies compared observations arise from incomplete representation emissions and their source-specific Seasonal cycles a...

5-Lipoxygenase (5-LO) catalyzes leukotriene (LT) biosynthesis by a mechanism that involves interactions with 5-lipoxygenase activating protein (FLAP) and coactosin-like protein (CLP). 5-LO splice variants were recently identified in human myeloid and lymphoid cells, including the catalytically inactive ∆13 isoform (5-LO∆13) whose transcript lacks exon 13. 5-LO∆13 inhibits 5-LO product biosynthe...

Using data from atmospheric neutrino mixing, and a simple functional form for mixing angles, the absolute values of three neutrino masses are calculated: m3 = 5.37 × 10 −2 eV, m2 = 1.94 × 10 −2 eV, m1 = 1.46 × 10 −2 eV. The quantities relevant for solar neutrino mixing are calculated: (m22 −m 2 1) = 1.63 × 10 eV, with non-maximal mixing tan θsol = 0.56. The analysis gives a suggestion of a dyna...

We present a characterization of supercompactness measures for ω1 in L(R), and of countable products of such measures, using inner models. We give two applications of this characterization, the first obtaining the consistency of δ13 = ω2 with ZFC+AD , and the second proving the uniqueness of the supercompactness measure over Pω1 (λ) in L(R) for λ > δ21. Starting with the work of Steel [13] it b...