A novel synthetic strategy leading to 3-acetamido-3-deoxy-D-psicofuranose 9 is presented. The latter compound, after some manipulations, was transformed into fully protected 3-acetamido-3-deoxy-D-psicofuranose 11 as a potential substrate for the synthesis of N-acetylglucosaminyltransferase inhibitors designed by computational methods. After the attempted thioglycosylation of 11 with EtSH in the...

Derivatives of the fully twisted bicyclic amide 7-hypoquinuclidone are synthesized using a Schmidt-Aubé reaction. Their structures were unambiguously confirmed by X-ray diffraction analysis and extensive spectroscopic characterization. Furthermore, the stability and chemical reactivity of these anti-Bredt amides are investigated. 7-Hypoquinuclidonium tetrafluoroborate is shown to decompose to a...

The first example of the boron Lewis acid catalyzed C(sp2)-H functionalization of cyclic enones was achieved using diazoacetates. The insertion of the carbon atom of diazoacetates utilizes BF3•Et2O or a newly designed oxazaborolidinium ion as a catalyst to afford β-functionalized cyclic enones from simple cyclic enones in a single step and high yields. The reaction mechanism was investigated wi...

Schiff bases are aldehyde or ketone like compounds in which the carbonyl group is replaced by an imine or azomethine group. They are widely used for industrial purposes and also exhibit a broad range of biological activities. The reaction is acid catalysed, however only aldehydes and ketones which do not aldolize easily in acidic media, can be condensed with amines in presence of strong acid ca...

the knoevenagel condensation of aromatic aldehydes with barbituric acid, dimedone and malononitrile occurred in the presence of bf3/nano-γ-al2o3 at room temperature in ethanol. this catalyst is characterized by powder x-ray diffraction (xrd), fourier transform infrared spectroscopy (ft-ir), thermal gravimetric analysis (tga), field emission scanning electron microscopy (fesem) and energy-disper...

Usually, the ion implantation gases used in semiconductor production are required to be extremely high purity. Due presence of trace CO2 electronic special gas BF3, quality material is significantly affected, which makes it crucial impose control on content. Unlike a series blank adsorbents reported other studies, zinc-loaded prepared this study intended for adsorption from CO2/BF3. Firstly, ma...