Glycine (Gly) residues are particularly susceptible to hydrogen abstraction; which results in the formation of the capto-dative stabilized Cα-centered Gly radical (GLR) on the protein backbone. We examined the effect of GLR formation on the structure of the Trp cage; tryptophan zipper; and the villin headpiece; three fast-folding and stable miniproteins; using all-atom (OPLS-AA) molecular dynam...

The generalized likelihood ratio (GLR) test is a widely used method for detecting abrupt changes in linear systems and signals. In this paper the marginalized likelihood ratio (MLR) test is introduced for eliminating three shortcomings of GLR, while preserving its applicability and generality. Firstly, the need for a user-chosen threshold is eliminated in MLR. Secondly, the noise levels need no...

The code generator in a compiler attempts to match a subject tree against a collection of tree-shaped patterns for generating instructions. Tree-pattern matching may be considered as a generalization of string parsing. We propose a new generalized LR (GLR) parser, which extends the LR parser stack with a parser cactus. GLR explores all plausible parsing steps to find the least-cost matching. GL...

| The generalized likelihood ratio (GLR) test is a widely used method for detecting abrupt changes in linear systems and signals. In this paper the marginalized likelihood ratio (MLR) test is introduced for eliminating three shortcomings of GLR, while preserving its applicability and generality. Firstly, the need for a user-chosen threshold is eliminated in MLR. Secondly, the noise levels need ...

The generalized likelihood ratio (GLR) test has been studied for the detection and estimation of a jump in linear systems, where the choices of the window size for the online implementation and of the threshold have been recognized as key problems. This paper proposes a deadbeat observer based GLR test for linear time invariant (LTI) systems. The necessary window size is automatically determine...

This paper proposes the UGLR parser as an extension of the GLR parser. A UGLR parser is powerful enough to parse deterministically any phrase structure language if it is in the class of recursive languages and can parse any context free language as fast as the conventional GLR parser. Natural language processing often requires a parser for languages belonging to classes larger than that of cont...

This paper describes GLR*, a parsing system based on Tomita's Generalized LR parsing algorithm, that was designed to be robust to two particular types of extra-grammaticality: noise in the input, and limited grammar coverage. GLR* attempts to overcome these forms of extra-grammaticality by ignoring the unparsable words and fragments and conducting a search for the maximal subset of the original...

alpha-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-type glutamate receptors (AMPARs) mediate excitatory neurotransmission at neuronal synapses, and their regulated localization plays a role in synaptic plasticity. In Caenorhabditis elegans, the PDZ and PTB domain-containing protein LIN-10 is required both for the synaptic localization of the AMPAR subunit GLR-1 and for vulval fate...

ادغام داده‌ها بین حسگرهای مختلف می‌تواند موجب استخراج اطلاعات با دقت و کیفیت بالاتر گردد بهبود تشخیص تهدیدهای هسته‌ای را به همراه داشته باشد. در این تحقیق، ردیابی چشمه متحرک استفاده از تلفیق داده­های سیستم آشکارساز پرتوی دوربین نظارتی مورد مطالعه قرار گرفت است. بدین منظور الگوریتمی جهت ایجاد همبستگی تصاویر دریافتی توسط شمارش طراحی شده است تا مسیر حرکت جسمی که بیش­ترین ثبت آشکارسازی دارد عنوان ا...

Retrograde transport is a critical mechanism for recycling certain membrane cargo. Following endocytosis from the plasma membrane, retrograde cargo is moved from early endosomes to Golgi followed by transport (recycling) back to the plasma membrane. The complete molecular and cellular mechanisms of retrograde transport remain unclear. The small GTPase RAB-6.2 mediates the retrograde recycling o...