In mouse melanocytes, myosin Va is recruited onto the surface of melanosomes by a receptor complex containing Rab27a that is present in the melanosome membrane and melanophilin (Mlp), which links myosin Va to Rab27a. In this study, we show that Mlp is also a microtubule plus end-tracking protein or +TIP. Moreover, myosin Va tracks the plus end in a Mlp-dependent manner. Data showing that overex...

In this paper a new scheme of feature ranking and hence feature selection using a Multilayer Perceptron (MLP) Network has been proposed. The novelty of the proposed MLP-based scheme and its difference from another MLP-based feature ranking scheme have been analyzed. In addition we have modified an existing feature ranking/selection scheme based on fuzzy entropy. Empirical investigations show th...

The paper presents an S-Transform based multilayer perceptron neural network (MLP) classifier for the identification of power quality (PQ) disturbances.The proposed method is used to extract the three input features (Standard deviation, peak value and variances) from the distorted voltage waveforms simulated using parametric equations. The features extracted through S-transform are trained by a...

Systems (DEMS) is proposed. This MLP algorithm uses a gradient metric based on hardware-software cost and performance as the core metric for selection of optimal partitions and consists of three nested levels. The innermost level is a simple binary search that allows quick evaluations of a large number of possible partitions. The middle level iterates over different possible allocations of proc...

The main goal of this paper is to compare the performance which can be achieved by five different approaches analyzing their applications’ potentiality on real world paradigms. We compare the performance obtained with (1) Multi-network RBF/LVQ structure (2) Discrete Hidden Markov Models (HMM) (3) Hybrid HMM/MLP system using a Multi LayerPerceptron (MLP) to estimate the HMM emission probabilitie...

Classification of heart sound signals to normal or their classes of disease are very important in screening and diagnosis system since various applications and devices that fulfilling this purpose are rapidly design and developed these days. This paper states and alternative method in improving classification accuracy of heart sound signals. Standard and improvised Multi-Layer Perceptron (MLP) ...

Conventional MLP classifiers used in phonetic recognition and speech recognition may encounter local minima during training, and they often lack an intuitive and flexible adaptation approach. This paper presents a hybrid MLP-SVM classifier and its associated adaptation strategy, where the last layer of a conventional MLP is learned and adapted in the maximum separation margin sense. This struct...

In humans, cytoskeletal dystrophin and muscle LIM protein (MLP) gene mutations can cause dilated cardiomyopathy, yet these mutations may have different effects in mice, owing to increased accumulation of other, compensatory cytoskeletal proteins. Consequently, we characterized left-ventricular (LV) morphology and function in vivo using high-resolution cine-magnetic resonance imaging (MRI) in 2-...

We use a multi-layer perceptron (MLP) to transform cepstral features into features better suited for speaker recognition. Two types of MLP output targets are considered: phones (Tandem/HATS-MLP) and speakers (Speaker-MLP). In the former case, output activations are used as features in a GMM speaker recognition system, while for the latter, hidden activations are used as features in an SVM syste...