Although resveratrol exerts manifold antitumorigenic effects in vitro, its efficacy against malignancies in vivo seems limited. This has been increasingly recognized in recent years and has prompted scientists to search for structurally related compounds with more promising anticarcinogenic and/or pharmacokinetic properties. A class of structurally modified resveratrol derivatives, so-called re...

OBJECTIVES We aimed to evaluate the ability of vasodilator myocardial contrast echocardiography (MCE) to detect significant infarct-related artery (IRA) stenosis and multivessel disease (MVD) after thrombolysis. BACKGROUND The detection of residual IRA stenosis subtending significant viable myocardium and the identification of MVD may help to triage patients who may benefit from mechanical re...

The paper introduces ensembles of accumulate-repeat-accumulate (ARA) codes which asymptotically achieve capacity on the binary erasure channel (BEC) with bounded complexity per information bit. It also introduces symmetry properties which play a central role in the construction of capacity-achieving ensembles for the BEC. The results here improve on the tradeoff between performance and complexi...

AIMS Randomized trial to assess change in left ventricle ejection fraction (LVEF) and myocardial perfusion in patients with acute myocardial infarction (AMI) of anterior wall treated with bone marrow stem cells (BMSCs), compared with control group-from baseline in the acute phase up to 12 months of follow-up. METHODS AND RESULTS Forty-five patients were randomized 2:1 to BMSC group (n= 31) or...

Jasper Rine pays tribute to a distinguished career spanning several fields and a personality that was a legend among the many great teachers at UCSF.

BACKGROUND Recently, a chronic total occlusion (CTO) in a non-infarct-related artery (non-IRA) and not multivessel disease (MVD) alone was identified as an independent predictor of mortality after ST elevation myocardial infarction (STEMI). Patients with diabetes mellitus (DM) constitute a patient group with a high prevalence of MVD and high mortality after STEMI. The prevalence of CTO in a non...

OBJECTIVES This study assessed the degree of endothelial dysfunction in post-acute myocardial infarction (AMI) and its subsequent status in the infarct-related artery (IRA) in patients treated with thrombolysis. BACKGROUND Coronary flow reserve alterations in the IRA after thrombolysis have been described, but the endothelium-dependent vasomotion has not been investigated, to date. METHODS ...

www.aana.com/aanajournalonline Upcoming Book: Ira P. Gunn To the editor: At the upcoming Annual Congress in Salt Lake City the AANA will release the newly published book Ira P. Gunn, Nurse Anesthetist. For my co-editors and me, work on the book was a true labor of love and an exploration of the genius Ira was. We each knew Ira in different ways and at somewhat different times, but we each learn...

In this research paper, an experimental breakthrough curve for citric acid in an adsorption recovery process was determined by an ion-exchange resin in 20, 35, 55 °C. Also, a mathematical model for breakthrough curve was presented. Among ion exchange resins that have been experienced, many weak and strong basic anionic resins are available such as, IRA-92, IRA-93, IRA-420 and IRA-458 and all of...

The issue of multivessel percutaneous revascularization in ST-segment elevation myocardial infarction (STEMI) is currently unambiguously decided by the guidelines: with the exception of cardiogenic shock, percutaneous coronary intervention (PCI) should be limited to the culprit stenosis in the infarct-related artery (IRA), with the class and level of evidence IIaB in the ESC and IIIB in ACCF/ /...