Colon cancer is one of the major causes of cancer-related death in the Western world. Although cytotoxic chemotherapeutic agents are available to treat the disease, these agents become ineffective as the disease advances to an invasive state. An alternative but viable approach to reduce the incidence of this deadly disease is then, to increase the dietary intake of relatively non-toxic fruits a...

Objective: The objective of the present study was to evaluate the acute and sub-acute toxicity profile of ethanolic extracts of Punica granatum (L).whole fruit (EPWF) and seeds (EPS) and synthetic ellagic acid (EA) in Swiss albino mice following OECD guidelines. Methods: In acute toxicity study, mice were orally administered 2000 mg/kg body weight of extracts and synthetic compound. In subacute...

AIM This study evaluated the in vitro antibacterial effects of the formulated Punica granatum (PG) gel against Streptococcus mutans, Streptococcus sanguinis, and Lactobacillus casei. MATERIALS AND METHODS The PG extract was dissolved in water at 500 mg/mL. High performance liquid chromatography (HPLC) was used for identification and quantification of chemical marker punicalagin. Minimum bacte...

The pomegranate, Punica granatum L., is an ancient, mystical, unique fruit borne on a small, long-living tree cultivated throughout the Mediterranean region, as far north as the Himalayas, in Southeast Asia, and in California and Arizona in the United States. In addition to its ancient historical uses, pomegranate is used in several systems of medicine for a variety of ailments. The synergistic...

This study evaluated the production of five new pomegranate varieties (MAP 14 , AKP15 , DMWP 2, NMRP 7 and JBP 1), being all indigenous to Southeastern India where the species shows high variability. A morphological and organoleptic characterisation of the edible portion of the seeds were investigated. Some chemical characteristics of the juice, including total soluble solids, pH, acidity and m...

Four Chinese pomegranate (Punica granatum L.) cultivars were analyzed for their individual flavonols and flavones (in fruit peel extracts) using High Performance Liquid Chromatography (HPLC), with changes in flavonols and flavones as occurring during fruit development. The results revealed the presence of kaempferol, quercetin, myricetin, luteolin, and apigenin in all the four cultivars. In add...

background & aim: punica granatum l. (pomegranate) is a widely used plant that has high nutritional value .this study evaluated prevention effect of hydro alcoholic extract of punica granatum flower and leaves ethylene glycol-induced nephrolithiasis in wistar rats. experimental: 20 male wistar rats were randomly divided into 4 equal groups. group i served as positive control and received distil...

The chemical composition and minerals analysis of four different plant species viz., Hippophae rhamnoides, Azadirachta indica, Punica granatum and Ocimum sanctum leaves were studied. In the nutritional analysis the Punica granatum was found enriched source of ectin, crude fiber, sugar and vitamin C as compare with other targeted plant leaves. The fat contents was also found in valuable quantity...

BACKGROUND AND AIM: Streptococcus mutans (S. mutans)is a well-known bacterial cause of dental caries. The aim of this study was to develop an herbal mouthwash with anti-biofilm activity and compare it with a commercial preparation containing 2% chlorhexidine. METHODS: The main components of the mouthwashes included Punica...