Near-infrared surface-enhanced Raman scattering (NIR SERS) imaging is now a promising molecular imaging technology due to its narrow spectral bandwidth, low background interference and deep imaging depth. In this work, we report a novel strategy for fabrication of NIR SERS nanoprobes without using any expensive and highly toxic organic dyes. Multifunctional conducting polymer (CP) materials, se...

In the 1980s, near infrared (NIR) spectroscopy was first applied in agriculture in China. In the 1990s, NIR spectroscopy was gradually accepted as a fascinating analytical technology by some analytical scientists and factory managers, because it possesses several attractive advantages, such as needing no or minimal sample preparation, low cost, high speed and high efficiency. In the 2000s, NIR ...

BACKGROUND Colon cancer is one of the major causes of death in the Western world. Early detection significantly improves long-term survival for patients with the disease. Near- infrared (NIR) fluorescent nanoparticles hold great promise as contrast agents for tumor detection. NIR offers several advantages for bioimaging compared with fluorescence in the visible spectrum, ie, lower autofluoresce...

In this paper, we present a method for fusing face and iris biometrics using single near infrared (NIR) image. Fusion of NIR face and iris modalities is a natural way of doing multi-model biometrics because they can be acquired in a single image. An NIR face image is taken using a high resolution NIR camera. Face and iris are segmented from the same NIR image. Face and iris features are then ex...

Near infrared photoimmunotherapy (NIR-PIT) is a newly-developed cancer therapy in which a monoclonal antibody is conjugated to a near-infrared photoabsorber, IR700 to form an antibody photoabsorber conjugate (APC). After the APC binds to cancer cells expressing the cognate antigen, exposure to NIR light results in rapid, highly selective necrotic cell death of the cancer cells with minimal off-...

BACKGROUND AND OBJECTIVE Humans are increasingly exposed to near-infrared (NIR) radiation from both natural (eg, solar) and artificial (eg, electrical appliances) sources. Although the biological effects of sun and ultraviolet (UV) exposure have been extensively investigated, the biological effect of NIR radiation is still unclear. We previously reported that NIR as well as UV induces photoagin...

The invasive nature and adverse side effects of surgery and chemotherapy have limited the efficacy of cancer treatment. Our laboratory has incorporated tissue penetrating near infrared (NIR) light and NIR-sensitive nanoparticles to develop a minimally invasive drug delivery system. NIR-activated release of an anticancer drug from NIR-sensitive nanoparticles could potentially reduce deleterious ...