Hybrid FEM/MoM methods combine the finite element method (FEM) and the method of moments (MoM) to model inhomogeneous unbounded problems. These two methods are coupled by enforcing field continuity on the boundary that separates the FEM and MoM regions. Hierarchical higher-order tangential vector finite elements (TVFE’s) are of practical interest because they can be easily combined with low-ord...

Method of moments (MoM) has recently become an appealing alternative to standard iterative approaches like Expectation Maximization (EM) to learn latent variable models. In addition, MoM-based algorithms come with global convergence guarantees in the form of finite sample bounds. However, given enough computation time, by using restarts and heuristics to avoid local optima, iterative approaches...

Approximately 1 million metal-on-metal (MoM) hip prostheses have been implanted worldwide to alleviate pain, restore hip function, and improve overall quality of life. These implants contain femoral and acetabular bearing surfaces that are typically composed predominantly of cobalt (Co) and chromium (Cr). Although the majority of MoM hip replacements have been successful, multiple recent report...

Disclosures: G W Blunn (5), Roberta Ferro Godoy (N), Hannah Wilson (3A Zimmer Biomet), Imran Khan (3A Zimmer Biomet), M J Coathup (N) INTRODUCTION: Data from the National Joint Registry of England and Wales (NJR) has shown that hip replacements with metal-onmetal (MoM) bearings, have significantly higher revision rates compared to metal-on-polyethylene (MoP). According to the NJR approximately ...

Background and purpose - It is unclear whether metal particles and ions produced by mechanical wear and corrosion of hip prostheses with metal-on-metal (MoM) bearings have systemic adverse effects on health. We compared the risk of heart failure in patients with conventional MoM total hip arthroplasty (THA) and in those with metal-on-polyethylene (MoP) THA. Patients and methods - We conducted a...

OBJECTIVES Hips with metal-on-metal total hip arthroplasty (MoM THA) have a high rate of adverse local tissue reactions (ALTR), often associated with hypersensitivity reactions. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) measures tissue perfusion with the parameter Ktrans (volume transfer constant of contrast agent). Our purpose was 1) to evaluate the feasibility of DCE-MRI ...

BACKGROUND Conventional total hip replacement (THR) may be felt to carry too high a risk of failure over a patient's lifetime, especially in young people. There is increasing interest in metal on metal hip resurfacing arthroplasty (MoM) as this offers a bone-conserving option for treating those patients who are not considered eligible for THR. We aim to evaluate the effectiveness of MoM for tre...

OBJECTIVE To investigate whether maternal serum levels of adiponectin in the first trimester are altered in pregnancies that subsequently deliver small for gestational age (SGA) neonates. METHODS Maternal serum adiponectin and pregnancy-associated plasma protein A (PAPP-A) were measured at 11-13 weeks' gestation in 50 singleton normotensive pregnancies that delivered SGA neonates and 300 non-...

Philips Mobile Obstetrics Monitoring (MOM) is a software solution that allows community healthcare workers to perform antenatal risk stratification, receive diagnostic assistance, and assess a patient’s progress via a mobile device to enhance maternal care in community settings. With MOM, ObGyns and midwives jointly review and manage each case, facilitating timely referral of the patient to an ...

Expression of the bacteriophage Mu mom gene is subject to posttranscriptional regulation by the phage com gene product. We have used mom-lacZ translational fusion genes to define the sequence requirements for stimulation of mom expression by Com. We show that the mom translation initiation region (TIR) is inactive in the absence of Com. We suggest that this repressed state is due to mRNA second...