Rationale: The ? 2 -adrenoceptor (? -AR), a prototypical GPCR (G protein-coupled receptor), couples to both G s and i proteins. Stimulation of the -AR is beneficial humans animals with heart failure presumably because it activates downstream -PI3K-Akt cell survival pathway. Cardiac signaling can be regulated by crosstalk or heterodimerization other GPCRs, but physiological pathophysiological si...

The effects of forage type and forage:concentrate ratio (F:C) on apparent nutrient digestibility, ruminal fermentation, and microbial growth were investigated in goats. A comparison between liquid (LAB) and solid (SAB)-associated bacteria to estimate microbial N flow (MNF) from urinary purine derivative excretion was also examined. Treatments were a 2 x 2 factorial arrangement of forage type (g...

The lead-zinc-barium deposits of the southern Benue Trough, Nigeria belong to a suite clastic dominated fracture filling hydrothermal vein deposits. alteration types and spread are poorly known yet required aid exploration. Band ratio composites (BRC), Principal Component Analysis (PCA), Minimum Noise Fraction (MNF) were applied full scene Advanced Spaceborne Thermal Emission Reflection Radiome...

expensive to provide these maps  with field measurements  therefore  it is better to use new methods. this study provides a lithological and alteration mapping units with dominant minerals based on hyperspectral images of eo1-hyperion satellite. to do so, two different zones  were  investigated:  the  cuprite-nevada  and  mozahem  volcano  in  iran  which  have suitable conditions for our study...

The Nayband strike-slip fault forms the western margin of the micro-continental Lut block in Eastern Iran. Neogene and Quaternary mafic volcanic rocks collected near Tabas, along the northern part of the fault (NNF; 15 Ma), and further to the south, along the middle part of the fault (MNF; 2 Ma), are within-plate sodic-series alkali olivine basalts with high TiO2 and up to >16% normative nephel...

Products of the nodule cytosol in vivo dark [(14)C]CO(2) fixation were detected in the plant cytosol as well as in the bacteroids of pea (Pisum sativum L. cv "Bodil") nodules. The distribution of the metabolites of the dark CO(2) fixation products was compared in effective (fix(+)) nodules infected by a wild-type Rhizobium leguminosarum (MNF 300), and ineffective (fix(-)) nodules of the R. legu...

In this paper we prove that the maximal operator of the Marcinkiewicz means of two-dimensional integrable functions with respect to the Walsh–Kaczmarz system is of weak type (1, 1). Moreover, the Marcinkiewicz means Mnf converge to f almost everywhere, for any integrable function f. © 2006 Elsevier Inc. All rights reserved.

1 Children's Hospital, University of Tuebingen, Tuebingen, Germany 2 Benaroya Research Institute, Virginia Mason Research Center, Seattle, USA 3 Department of Transfusion Medicine, University of Tuebingen, Tuebingen, Germany 4 Medical and Natural Sciences Research Centre (MNF), University of Tuebingen, T bingen, Germany 5 Department of Pediatrics and Pediatric Rheumatology, Olgahospital, Stuttg...