Introduction: The infection by Trypanosoma cruzi is a public health problem and there no effective treatment currently. Immunomodulatory effects of Atropa belladonna may offer benefits1 Objective: To evaluate the effect A. in murine T. cruzi. Methodology: experiment was blind, controlled randomized draw. Eighty five Swiss male mice, at 8 weeks age, were infected with 1400 blood trypomastigotes ...

Gerlllplaslll 01" ;/1 v;tro derived plantlels of Atroptl baeticfl was lIlainlained by cold storage al 4°C in darkness for six 1Il0nths. Tite response of Ihe cold stored gcrlllplasm to growing culture co nditions was sludied on Murasltige & Skoog mediullI supplelllented wilh BAP (0.66 mg r ), NAA (0.24 mg r\ inosilol (100 mg r ), Ihiamine (1 mg 1'1) :Hul 3% sucrose durillg a six month periodo Tl...

The tropane alkaloids, hyoscyamine and scopolamine, are medicinal compounds that are the active components of several therapeutics. Hyoscyamine and scopolamine are synthesized in the roots of specific genera of the Solanaceae in a multistep pathway that is only partially elucidated. To facilitate greater understanding of tropane alkaloid biosynthesis, a de novo transcriptome assembly was develo...

There is an increasing use of herbal remedies and medicines, with a commonly held belief that natural substances are safe. We present the case of a 50-year-old woman who was a trained herbalist and had purchased an 'Atropa belladonna (deadly nightshade) preparation'. Attempting to combat her insomnia, late one evening she deliberately ingested a small portion of this, approximately 50 mL. Unint...