Objectives: Eβ-thalassemia, the most serious form of HbE syndromes, may develop pre-diabetes (PD) and diabetes mellitus (DM), together constituting abnormal glucose homeostasis (AGH) as an endocrinopathy. This study aims to assess AGH prevalence pathogenesis in this thalassemia subtype. Material Methods: A cross-sectional was conducted at a tertiary care hospital from February 2017 December 201...

Growing evidence supports that air pollution exposure has become a risk factor of type II diabetes mellitus through the induction insulin resistance (IR), but presented findings did not provide consistent relationship between and IR in temporal scale magnitude. Reported associated with exposure, branched-chain amino acids (BCAAs) blood might modify association IR. We took advantage an existing ...

4.3. (i) Since HomA(A (I),M) ∼= M (I) for a set I and ⊕ is exact, it is clear that HomA(A (I),−) is exact, i.e. A(I) is projective. (ii) “Only if” part: Let A(P ) = ⊕ p∈P Ap be the free A-module indexed by P and ψ : A (P ) → p be the A-homomorphism such that ψ(1p) = p. Then ψ is surjective. If P is projective, then ψ has a section, i.e. an A-homomorphism φ : P → A(P ) such that ψ ◦ φ = idP . Th...

intake of socially undesirable sucrosecontaining foods. These assumptions would never be reliable. Thus, we recommended caution when interpretation of results from this part of our study. The last point raised by Buyken and Liese was that alcohol intake may predict glycemic index of the diet and hence affect the estimates of glycemic index and glycemic load. The reported associations are relati...

OBJECTIVE Insulin resistance (IR) and associated metabolic abnormalities are increasingly being reported in the adolescent population. Cut-off value of homeostasis model of assessment IR (HOMA-IR) as an indicator of metabolic syndrome (MS) in adolescents has not been established. This study aimed to investigate IR by HOMA-IR in urban Indian adolescents and to establish cut-off values of HOMA-IR...

BACKGROUND Insulin-resistance is associated with cardiovascular disease but it is not used as a marker for disease in clinical practice. AIMS To study the association between the homeostatic model assessment (HOMA-IR) and triglyceride/HDLc ratio (TG/HDLc) with the presence of coronary artery disease in patients submitted to cardiac catheterization. METHODS In a cross-sectional study, 131 pa...

OBJECTIVE To assess the individual variability of HOMA and QUICKI indexes for the assessment of insulin resistance, using three fasting blood samples obtained within 30 minutes. RESEARCH METHODS & PROCEDURES Data from 80 participants aged 41.5 ± 15 years (26 females), who underwent an oral glucose tolerance test to calculate Matsuda index, were used. Every participant had three fasting blood ...

OBJECTIVE To determine the association of insulin sensitivity and pancreatic beta-cell function parameters assessed by the homeostasis model assessment (HOMA) and glycemic control, and their potential utilization in the clinical care of patients with type 2 diabetes mellitus. MATERIAL AND METHOD The HOMA indices were assessed in 204 (62 males, 142 females) type 2 diabetic outpatients aged 60....

BACKGROUND Homeostasis model assessment of insulin resistance (HOMA-IR) is a surrogate estimate of directly measured insulin resistance that been robustly proven to be associated with diabetes and cardiovascular disease. The purpose of this study was to evaluate the use of several simple indicators to identify postmenopausal women with insulin resistance estimated by HOMA-IR. METHODS We recru...

Introduction and aim. Thyroid hormones play an important role in glucose metabolism as many metabolic events. The aim of our study is to evaluate the relationship between subclinical hypothyroidism (SCH) insulin resistance, especially obese women. Material methods. Newly diagnosed SCH patients with body mass index (BMI) ≥30 who applied outpatient clinic March 2021 October 2021, euthyroid women ...