Bioactive glass has found extensive application as an orthopedic and dental graft material and most recently also as a tissue engineering scaffold. Here we report an initial investigation of the in vitro antibacterial properties of AgBG, a novel bioactive glass composition doped with Ag(2)O. The bacteriostatic and bactericidal properties of this new material and of two other bioactive glass com...

Abstract — Fe2O3 substituted 45S5 bioactive glasses were prepared. Glass derived Bioactive Glass ceramics were obtained through controlled crystallization of bioactive glasses. Nucleation and crystallization regimes were determined by the parameters obtained from differential thermal analysis (DTA) of bioactive glasses. The formed crystalline phases in bioactive glass ceramics were identified u...

In recent years, there has been considerable interest in the potential antibacterial properties that bioactive glasses may possess. However, there have been several conflicting reports on the antibacterial efficacy of 45S5 Bioglass(®). Various mechanisms regarding its mode of action have been proposed, such as changes in the environmental pH, increased osmotic pressure, and 'needle-like' sharp ...

Tissue engineering is a multi-disciplinary field, which aims to apply innovative biomaterials to replace or restore ill or damaged tissues of the human body, such as skin and bones. In particular, porous scaffolds are used as temporary 3D templates to support cell attachment and proliferation during the spontaneous regeneration of natural tissues and this approach is particularly promising for ...