We report on characterization of a 170,000 Da glycoprotein found exclusively in the PNS. We refer to this protein as the Schwann cell membrane glycoprotein (SAG). SAG contains the HNK-1 carbohydrate, which is considered by some to be a marker of adhesion molecules. Its N-terminal sequence is not similar to previously known polypeptide sequences. SAG is found exclusively in the PNS, is present i...

This study presents optimal placement of voltage sag monitors based on new Sag Occurrence Index (SOI) which ensures observability even in case of monitor failure or line outages. Multiple solutions for optimal placement of voltage sag monitors for voltage sag detection have been obtained by genetic algorithm approach such that observability of the whole system is guaranteed. A new Sag Occurrenc...

Voltage sags in the electric power system are mostly due to faults in the power system. Voltage sag is characterized by its magnitude (the retained voltage), phase-angle jump, unbalance in the sag in the three phases, and duration. Type of transformers in the electrical system is the important parameter influencing the characteristic of sag at the node where sensitive loads are connected. For s...

Horizontal gene transfer from retroviruses to mammals is well documented and extensive, but is rare between unrelated viruses with distinct genome types. Three herpesviruses encode a gene with similarity to a retroviral superantigen gene (sag) of the unrelated mouse mammary tumour virus (MMTV). We uncover ancient retroviral sags in over 20 mammals to reconstruct their shared history with herpes...

The number of lifters of mill shell liners, mill rotation speed, and filling percentage of grinding media are three of the most important parameters influencing the charge behavior and the trajectory of ball motion inside the SAG mills, and consequently, their performance. In this paper, the milling operation of pilot-scale SAG mills using the discrete element method (DEM) is investigated. Firs...

Salivary agglutinin (SAG), also known as gp340 or SALSA, is a glycoprotein encoded by the Deleted in Malignant Brain Tumours 1 gene and is abundantly present in human saliva. SAG aggregates bacteria and viruses, thereby promoting their clearance from the oral cavity. The mucosa lining the oral cavity contains dendritic cells (DC) and Langerhans cells (LC), which express the C-type lectin recept...

Staphylococcus aureus, the most common cause of wound infection, produces several exotoxins, including superantigens (SAgs). SAgs are the potent activators of the immune system. Given this unique property, we hypothesized that SAgs produced by S. aureus in wounds would have local, as well as systemic immunologic effects. We tested our hypothesis using a novel staphylococcal skin wound infection...

Rheology is one of the key drilling fluid properties for controlling sag. Yet, the current understanding of the sag-rheology relationship is limited to a few general guidelines for reducing sag in the field. This paper reviews current understanding of sag and describes the initial stage of work aimed at finding a correlation between fluid rheology and sag performance under laboratory conditions...

The electric power distribution system must be designed to operate and supply acceptable level of electrical energy to customers. Power utilities must ensure that the power supply to customers is with voltage magnitude within standard levels. Other features like minimal interruptions and minimal system power loss also must be considered. Hence, the quality and reliability of supply must be main...

The inability of sodium antimony gluconate (SAG)-unresponsive kala-azar patients to clear Leishmania donovani (LD) infection despite SAG therapy is partly due to an ill-defined immune-dysfunction. Since dendritic cells (DCs) typically initiate anti-leishmanial immunity, a role for DCs in aberrant LD clearance was investigated. Accordingly, regulation of SAG-induced activation of murine DCs foll...