Aim: Cleft lip and palate (CLP) patients have a greater predisposition to tooth malformation, which could affect pulp volume. The aim of this study is evaluate the dental volume central incisors in 3D images between individuals with without CLP. Materials Methods: This retrospective case-control single-centered was recruited January 2016 October 2022. Ninety-four who were followed Institute Ort...

INTRODUCTION The antibacterial effect of ozone (O(3)) has been described in the extant literature, but the role of O(3) therapy in the treatment of certain types of infection remains controversial. OBJECTIVES To evaluate the effect of intraperitoneal (i.p.) O(3) application in a cecal ligation/puncture rat model on interleukins (IL-6, IL-10) and cytokine-induced neutrophil chemoattractant (CI...

The manipulation of CLP(<) programs in CLP(<) is severely limited, since equality for this language is not based on the syntactic structure of terms. We propose an extended language, CLP(< + M), which provides a basis for (a) coding terms in a form which allows arbitrary structural manipulation, and (b) converting between terms and their coded forms. Importantly, CLP(<+ M) may not only be used ...

Abstract Loess sequences of the Chinese Plateau (CLP) compose one most complete Neogene–Quaternary terrestrial paleoclimatic archives. Understanding CLP's sediment sources is critical to tracing Asian aridification, atmospheric circulation patterns, and monsoon evolution. Commonly, sediments that Quaternary strata CLP are considered largely homogeneous, thus numerous studies have applied a unif...

این پژوهش با الهام گرفتن از نتایج یک طرح مطالعاتی کاربردی، رویکرد سلسله­‌مراتبی جهت پیگیری فرایند توسعه تأمین‌کنندگان و حمایت تصمیمات موجود در هر مراحل آن ارائه‌ می‌کند. ابتدا، زمینه‌های تأمین نیازمند سپس واجد شرایط هریک زمینه‌ها به کمک تصمیم‌گیری چندشاخصه بهترین-بدترین مشخص می‌گردند. معیارهای شناسایی نیز مرور مطالعات پیشین بهره‌گیری نظرات خبرگان حوزه‌ی خرید استخراج‌شده‌اند. درنهایت، مدل ریاضی ...

The cyclic lipopeptide (CLP) has been known to inhibit proliferation and induce apoptosis in cancer cells. However, the molecular mechanisms involved in CLP-induced apoptosis are still uncharacterized in human leukemic K562 cells. The current study investigated the molecular mechanism of action of CLP, purified from Bacillus natto T-2. CLP-induced a sustained increase in concentration of intrac...

BACKGROUND Vascular hyporeactivity is observed in portal hypertensive animals and septic rats. The objective of this study was to investigate whether impairment of superior mesenteric artery vascular contractility in the portal hypertensive rat was further impaired after sepsis. METHODS Sepsis was induced by cecum ligation and puncture (CLP) in male portal hypertensive Sprague-Dawley rats tha...

INTRODUCTION Since the NF-κB pathway regulates both inflammation and host defense, it is uncertain whether interventions targeting NF-κB would be beneficial in sepsis. Based on the kinetics of the innate immune response, we postulated that selective NF-κB inhibition during a defined time period after the onset of sepsis would reduce acute lung injury without compromising bacterial host defense....

We previously established a bioassay method to screen for compounds that activate the promoter activity of p21(WAF1/CIP1), a potent inhibitor of cyclin-dependent kinases, in a p53-independent manner. As an activator of p21(WAF1/CIP1) promoter activity, we isolated cryptolepine (CLP: 5-methyl indolo (2,3b)-quiniine), an indoloquinoline alkaloid, from the traditional Ayurvedic medicinal plant Sid...

In hybrid solvers for combinatorial optimization, combining Constraint (Logic) Programming (CLP) and Mixed Integer Programming (MIP), it is important to have tight connections between the two domains. We extend and generalize previous work on automatic linearizations and propagation of symbolic CLP constraints that cross the boundary between CLP and MIP. We also present how reduced costs from t...