نتایج جستجو برای: مدل hec 1
تعداد نتایج: 2856252 فیلتر نتایج به سال:
RNA interference of pax2 inhibits growth of transplanted human endometrial cancer cells in nude mice
The development of human endometrial carcinoma (HEC) is a complex pathologic process involves several oncogenes and tumor suppressor genes. The full-length paired-box gene 2 (pax2), a recently discovered oncogene, promotes cell proliferation and growth and inhibits apoptosis of HEC cells. Here, we examined the effect of pax2 small interfering RNA (siRNA) on the growth of transplanted HEC cells ...
In this paper, we present a conceptual framework of human–elephant conflict (HEC) management embodying community aspects gleaned from the importance–performance analysis (IPA) for National Park in Vietnam. Nine approaches were proposed to prevent and mitigate HEC (HEC indicators), which six fell into different quadrants based on respective estimations farmer non-farmer respondents. Both levels ...
چکیده در محاسـبات هیدرولوژیکی یـک حوضه تعیین ارتباط بین بارش- رواناب بسیار مـهم است. محاسبهی دقیق بارش-رواناب در سطح حوضه به شناخت مؤلفهها و متغیرهای شکلدهندهی آن و همچنین استفاده از یک مدل مناسب وابسته است. در این مطالعه، بارش-رواناب پیوستهی حوضهی شهرچای ارومیه با استفاده از مدل هیدرولوژیکی HEC-HMS شبیهسازی شد. برای این منظور ابتدا مدل حوضهی آبخیز با استفاده از نقشهی DEM منطقهی مور...
Estrogen Regulates the Tumour Suppressor MiRNA-30c and Its Target Gene, MTA-1, in Endometrial Cancer
MicroRNA-30c (miR-30c) has been reported to be a tumour suppressor in endometrial cancer (EC). We demonstrate that miR-30c is down-regulated in EC tissue and is highly expressed in estrogen receptor (ER)-negative HEC-1-B cells. MiR-30c directly inhibits MTA-1 expression and functions as a tumour suppressor via the miR-30c-MTA-1 signalling pathway. Furthermore, miR-30c is decreased upon E2 treat...
شناخت حوزههای آبخیز جهت حفاظت آب و خاک و ارائۀ برنامهریزی مناسب در سطح حوزۀ آبخیز از اهمیت بالایی برخوردار است. شبیهسازی حوزههای آبخیز با استفاده از مدلهای رایانهای بهطور سریع در حال توسعه است و این مدلها ابزارهای ضروری برای فهم انسان از حوزۀ آبخیز و فرآیندهای هیدرولوژیکی هستند. در این تحقیق مدلهای بارش-رواناب HEC-HMS و IHACRES برای شبیهسازی هیدروگراف سیل در حوزۀ آبخیز کسیلیان با مساح...
The influence of adaptation to pH (from pH 5.0 to 9.0) on membrane lipid composition, verotoxin concentration, and resistance to acidic conditions in simulated gastric fluid (SGF) (pH 1.5, 37 degrees C) was determined for Escherichia coli O157:H7 (HEC, ATCC 43895), an rpoS-deficient mutant of ATCC 43895 (HEC-RM, FRIK 816-3), and nonpathogenic E. coli (NPEC, ATCC 25922). Regardless of the strain...
Cellulose based polymers have shown tremendous potential as drug delivery carrier for oral drug delivery system (DDS). Hydroxyethyl cellulose (HEC) and hydroxypropyl cellulose (HPC) are widely explored as excipients to improve the solubility of poorly water soluble drugs and to improve self-life of dosage form. This work is an attempt to modulate the physicochemical properties of these cellulos...
Chitosan-beta glycerophosphate-hydroxyethyl cellulose (CH-GP-HEC) is a biocompatible and biodegradable scaffold exhibiting a sol-gel transition at 37°C. Chondrogenic factors or mesenchymal stem cells (MSCs) can be included in the CH-GP-HEC, and injected into the site of injury to fill the cartilage tissue defects with minimal invasion and pain. The possible impact of the injectable CH-GP-HEC on...
For decades, performance has driven the high-end computing (HEC) community. However, as highlighted in recent exascale studies that chart a path from petascale to exascale computing, power consumption is fast becoming the major design constraint in HEC. Consequently, the HEC community needs to address this issue in future petascale and exascale computing systems. Current scientific benchmarks, ...
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