نتایج جستجو برای: مدل pra

تعداد نتایج: 123922  

Journal: :Gynecologic oncology 2005
Kimberly K Leslie Mary-Pat Stein Nirmala S Kumar Donghai Dai Janet Stephens Angela Wandinger-Ness Deborah H Glueck

OBJECTIVE These studies were undertaken to characterize the subcellular localization of the two major isoforms of progesterone receptors (PR), PRA and PRB, in endometrial cancer. METHODS Immunohistochemistry, immunoprecipitation, and confocal microscopy were performed using Hec50co and KLE endometrial cancer cell models expressing PRA or PRB as a consequence of transduction. The location of P...

Journal: :Transplantation 1989
T Weber I R Marino Y G Kang C D Esquivel T E Starzl R J Duquesnoy

Intraoperative blood requirements were analyzed in patients undergoing primary orthotopic liver transplantation and divided into two groups on the basis of panel reactive antibody of pretransplant serum measured by lymphocytotoxicity testing. One group of highly sensitized patients (n = 25) had PRA values of over 70% and the second group of patients (n = 26) had 0% PRA values and were considere...

Journal: :Molecular and cellular biology 1988
D J Klionsky L M Banta S D Emr

An inactive precursor form of proteinase A (PrA) transits through the early secretory pathway before final vacuolar delivery. We used gene fusions between the gene coding for PrA (PEP4) and the gene coding for the secretory enzyme invertase (SUC2) to identify vacuolar protein-sorting information in the PrA precursor. We found that the 76-amino-acid preprosegment of PrA contains at least two sor...

Journal: :Iranian journal of kidney diseases 2011
Ali Ghorbani Heshmatollah Shahbazian Ali Ehsanpour Asieh Aref

INTRODUCTION Both atorvastatin and mycophenolate mofetil (MMF) have been used for panel reactive antibodies (PRA) reduction in transplant candidates. The purpose of this study was to compare the effect of low-dose MMF and atorvastatin on PRA in sensitized hemodialysis patients waiting for kidney transplantation. MATERIALS AND METHODS A total of 40 adult patients with end-stage renal disease w...

Journal: :Clinical chemistry 2008
Frej Fyhrquist Outi Saijonmaa

Featured Article: Fyhrquist F, Soveri P, Puutula L, Stenman U-H. Radioimmunoassay of plasma renin activity. Clin Chem 1976;22:250 – 6. In the early 1970s there was a growing need for reliable and clinically useful methods for the determination of the activity of the renin-angiotensin system. Bioassay methods for renin activity, although valuable in early research, were too cumbersome and unreli...

Journal: :Investigative ophthalmology & visual science 1999
S M Petersen-Jones D D Entz D R Sargan

PURPOSE To screen the alpha-subunit of cyclic guanosine monophosphate (cGMP) phosphodiesterase (PDE6A) as a potential candidate gene for progressive retinal atrophy (PRA) in the Cardigan Welsh corgi dog. METHODS Single-strand conformation polymorphism (SSCP) analysis was used to screen short introns of the canine PDE6A gene for informative polymorphisms in members of an extended pedigree of P...

Journal: :Journal of clinical pathology 2001
P A Mote J F Johnston T Manninen P Tuohimaa C L Clarke

AIM The measurement of progesterone receptors (PR) is recommended as part of the clinical management of breast and endometrial cancers, and immunohistochemistry on formalin fixed tissue is now the method of choice. PR is expressed as two isoforms, PRA and PRB, and although both these proteins are expressed in hormone dependent cancers, there is evidence that a large proportion of tumours expres...

2016
Emma Wallace Ronald McDowell Kathleen Bennett Tom Fahey Susan M Smith

OBJECTIVES Emergency admission is associated with the potential for adverse events in older people and risk prediction models are available to identify those at highest risk of admission. The aim of this study was to externally validate and compare the performance of the Probability of repeated admission (Pra) risk model and a modified version (incorporating a multimorbidity measure) in predict...

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