نتایج جستجو برای: موش balbc

تعداد نتایج: 11978  

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 1999
J H Schiller G Bittner

Squalamine is a novel anti-angiogenic aminosterol that is postulated to inhibit neovascularization by selectively inhibiting the sodium-hydrogen antiporter exchanger. To determine how to most effectively use this agent in patients with cancer, we examined the antitumor effects of squalamine with or without cytotoxic agents in human lung cancer xenografts and correlated these observations with t...

2018
Claudia Schwarz Slaven Stekovic Miranka Wirth Gloria Benson Philipp Royer Stephan J Sigrist Thomas Pieber Christopher Dammbrueck Christoph Magnes Tobias Eisenberg Tobias Pendl Jens Bohlken Theresa Köbe Frank Madeo Agnes Flöel

Supplementation of spermidine, an autophagy-inducing agent, has been shown to protect against neurodegeneration and cognitive decline in aged animal models. The present translational study aimed to determine safety and tolerability of a wheat germ extract containing enhanced spermidine concentrations. In a preclinical toxicity study, supplementation of spermidine using this extract did not resu...

2017
Ophélie Beaujean Filippo Locri Monica Aronsson Anders Kvanta Helder André

PURPOSE To assess iris neovascularization by uveal puncture of the mouse eye and determine the role of angiogenic factors during iris neovascularization. METHODS Uveal punctures were performed on BalbC mouse eyes to induce iris angiogenesis. VEGF-blockage was used as an anti-angiogenic treatment, while normoxia- and hypoxia-conditioned media from retinal pigment epithelium (RPE) cells was use...

ALAN B. McCRUDEN, KAZEM AHMADI-RENANI ,

One of the mechanisms involved in the regulation of the immune system by steroid hormones could be the monocytic-macrophage system. In this study the effect of the male hormone 5a-DHT on cytokine release by peritoneal macrophages (mΦ) of male and female NZB/BALBc mice was investigated. Macrophages from male mice activated with LPS produced a greater amount of IL-1β (21.8%) (p<0.05) and IL-...

زارع, صمد, قادری پاکدل, فیروز, قزلباش, باران, محمدحسن, زهیر,

Introduction: The probiotic strains of Lactic Acid Bacillus (LAB) not only affect gastrointestinal tract microflora and stimulate local immune system of this tract but also modify and stimulate systemic immunity by influence on lymph nodes and spleen. Several studies have shown the anti-tumor effect of these kinds of bacteria. This study was designed to assess the probiotic effects of lactobaci...

Journal: :journal of paramedical sciences 0
zarin sharifnia biothecnology department, school of medicine, tabriz university of medical sciences, tabriz nariman mosaffa immunology department, school of medicine, shahid beheshti university of medical sciences, tehran mahvash khodabandeh national institute of genetics engineering for biological researches, tehran roya yaraee immunology department, shahed university, tehran bahram kazemi cellular &amp; molecular research center, school of medicine, shahid beheshti university of medical sciences, tehran mojgan bandehpour cellular &amp; molecular research center, school of medicine, shahid beheshti university of medical sciences, tehran

there are more than 350 million individuals with hepatitis c in the world. one of the important problems in vaccine project is development of effective and suitable adjuvant in human vaccines. at present research we applied human βhsp90 protein as an adjuvant in recombinant hcv vaccine design. the thermal vector of pgp1-2 was used for human heat shock protein 90 expression. this protein injecte...

Journal: : 2022

زمینه و هدف: microRNA (miRNA) دستة جدیدی از شاخص‌های زیستی‌اند که در سطح سلولی مسیرهای پیام‌رسانی تغییرات ساختاری عملکردی قلبی درگیرند. همچنین تمرینات تناوبی شدید (HIIT) شامل وهله‌های فعالیت ورزشی نسبتاً با مدت زمان کوتاه است دوره‌های بازیافت فعال یا غیرفعال یکدیگر جدا شده‌اند، می‌تواند سبب بهبود آمادگی قلبی-تنفسی متغیرهای فیزیولوژیک متناظر آن افراد سالم شود. ازاین‌رو پژوهش حاضر نظر دارد اثر هشت...

پایان نامه :وزارت بهداشت، درمان و آموزش پزشکی - دانشگاه علوم پزشکی و خدمات بهداشتی درمانی استان مرکزی - دانشکده پزشکی 1387

این تحقیق تجربی بر روی 36 موش صحرایی نر و ماده تازه متولد شده نژاد wistar انجام گرفت در این تحقیق موش ها به شکل تصادفی به شش گروه تقسیم شدند که عبارت بودند از موش های ماده با تزریق پروژسترون، موش های نر با تزریق پروژسترون،موش های ماده با تزریق سزاموئید، موش های نر با تزریق سزاموئید و موش های نر و ماده کنترل. سپس گروه های پروژسترونی، پروژسترون را با غلظت 100 میلی گرم به ازاء هر کیلوگرم وزن حیوان...

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