نتایج جستجو برای: نقشهیابی qtl

تعداد نتایج: 8581  

Journal: :Journal of animal science 2010
C Duthie G Simm A Doeschl-Wilson E Kalm P W Knap R Roehe

The present study focused on the identification of epistatic QTL pairs for body composition traits (carcass cut, lean tissue, and fat tissue weights) measured at slaughter weight (140 kg of BW) in a 3-generation full-sib population developed by crossing Pietrain sires with a crossbred dam line. Depending on the trait, phenotypic observations were available for 306 to 315 F(2) animals. For the Q...

Journal: :Animal genetics 2009
G Hadjipavlou S C Bishop

To dissect age-dependent quantitative trait loci (QTL) associated with growth and to examine changes in QTL effects over time, the Gompertz growth model was fitted to longitudinal live weight data on 788 Scottish Blackface lambs from nine half-sib families. QTL were mapped for model parameters and weekly live weights and growth rates using microsatellite markers on chromosomes 1, 2, 3, 5, 14, 1...

Journal: :Animal genetics 2011
A K Esmailizadeh C A Morris N G Cullen Z A Kruk D S Lines S M Hickey P M Dobbie C D K Bottema W S Pitchford

A whole-genome scan was carried out in New Zealand and Australia to detect quantitative trait loci (QTL) for live animal and carcass composition traits and meat quality attributes in cattle. Backcross calves (385 heifers and 398 steers) were generated, with Jersey and Limousin backgrounds. The New Zealand cattle were reared and finished on pasture, whilst Australian cattle were reared on grass ...

Journal: :Journal of dairy science 2007
A J Buitenhuis M S Lund J R Thomasen B Thomsen V Hunnicke Nielsen C Bendixen B Guldbrandtsen

Lameness is an important factor for culling animals. Strong legs and feet improve herd life of dairy cows. Therefore, many countries include leg and feet conformation traits in their breeding programs, often as early predictors of longevity. However, few countries directly measure lameness related traits to include these in a breeding program. Lameness indices in 3 different lactations and 5 le...

2017
Jun-Ichi Suto Misaki Kojima

DDD/Sgn mice have significantly higher plasma lipid concentrations than C57BL/6J mice. In the present study, we performed quantitative trait loci (QTL) mapping for plasma total-cholesterol (CHO) and triglyceride (TG) concentrations in reciprocal F2 male intercross populations between the two strains. By single-QTL scans, we identified four significant QTL on chromosomes (Chrs) 1, 5, 17, and 19 ...

Journal: :Nucleic Acids Research 2006
Kremena V. Star Quingbin Song Andy Zhu Erwin P. Böttinger

Identifying genes that underlie quantitative trait loci (QTL) is a challenging task. Here, we present a new QTL software system, named QTL MatchMaker. The system is designed to integrate and mine QTL information across human, mouse and rat genomes and to annotate functional genomic data. It combines and organizes information from relevant public databases and publications and integrates QTL, ph...

Journal: :Genetics 2003
Garth R Brown Daniel L Bassoni Geoffrey P Gill Joseph R Fontana Nicholas C Wheeler Robert A Megraw Mark F Davis Mitchell M Sewell Gerald A Tuskan David B Neale

A long-term series of experiments to map QTL influencing wood property traits in loblolly pine has been completed. These experiments were designed to identify and subsequently verify QTL in multiple genetic backgrounds, environments, and growing seasons. Verification of QTL is necessary to substantiate a biological basis for observed marker-trait associations, to provide precise estimates of th...

Journal: :Genetics 2007
Stuart J Macdonald Anthony D Long

We develop and implement a strategy to map QTL in two synthetic populations of Drosophila melanogaster each initiated with eight inbred founder strains. These recombinant populations allow simultaneous estimates of QTL location, effect, and frequency. Five X-linked QTL influencing bristle number were resolved to intervals of approximately 1.3 cM. We confirm previous observations of bristle numb...

2011
Hsin-Chou Yang Chia-Wei Chen

Quantitative trait locus (QTL) mapping using deep DNA sequencing data is a challenging task. In this study we performed region-based and pathway-based QTL mappings using a p-value combination method to analyze the simulated quantitative traits Q1 and Q4 and the exome sequencing data. The aims were to evaluate the performance of the QTL mapping approaches that were used and to suggest plausible ...

2015
Honghua Zhao Jack C. M. Dekkers Max F. Rothschild Rohan L. Fernando Daniel S. Nettleton James M. Reecy

The goal of quantitative trait loci (QTL) mapping in livestock is to find genes underlying traits of economic importance for genetic improvement through marker assisted selection (MAS). The studies presented in this thesis address several important issues in QTL detection and fine mapping using candidate gene analysis and linkage disequilibrium (LD) mapping using high density genotyping. Tests ...

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