on 6p. In our own analysis, an intrageneic marker derived from this gene cosegregated with the adRP disease locus with zero recombination (lod score 5.46 at q = .00). Using the CEPH reference panel, we now report the mapping of the peripherin-RDS gene relative to other 6p markers in the CEPH data base. Incorporation of these data into a multipoint analysis produced a lod score for adRP of 8.21,...

Thirty four out of 750 patients entered into the Medical Research Council's (MRC) 9th Acute Myeloid Leukaemia Trial had more than 1% basophils (range 1-27%) often with bizarre granulation and primitive forms, a rare finding in this disease. Both normal and abnormal karyotypes were present including abnormalities of 6p, 12p, and the Philadelphia chromosome. Basophilia was found in both "monoline...

A graph is symmetric if its automorphism group acts transitively on the set of arcs of the graph. In this paper, we classify connected heptavalent symmetric graphs of order 6p for each prime p. As a result, there are three sporadic such graphs: one for p = 5 and two for p = 13.

We asymptotically determine the size of the largest family F of subsets of {1, . . . , n} not containing a given poset P if the Hasse diagram of P is a tree. This is a qualitative generalization of several known results including Sperner’s theorem. Introduction We say that a poset P is a subposet of a poset P ′ if there is an injective map f : P → P ′ such that a 6P b implies f(a) 6P ′ f(b). A ...

We have analyzed the effect of charged to neutral amino acid substitutions around the kinks flanking helices 4 and 6 of apoA-I and of the deletion of helix 6 on the in vivo activity of LCAT and the biogenesis of HDL. The LCAT activation capacity of apoA-I in vitro was nearly abolished by the helix 6 point (helix 6P-apoA-I[R160V/H162A]) and deletion {helix 6Delta-apoA-I[Delta(144-165)]} mutants,...